Surface-facilitated trapping by active sites: From catalysts to viruses
| dc.citation.articleNumber | 184106 | en_US |
| dc.citation.journalTitle | The Journal of Chemical Physics | en_US |
| dc.citation.volumeNumber | 155 | en_US |
| dc.contributor.author | Misiura, Mikita M. | en_US |
| dc.contributor.author | Berezhkovskii, Alexander M. | en_US |
| dc.contributor.author | Bezrukov, Sergey M. | en_US |
| dc.contributor.author | Kolomeisky, Anatoly B. | en_US |
| dc.contributor.org | Center for Theoretical Biological Physic | en_US |
| dc.date.accessioned | 2021-12-01T18:30:37Z | en_US |
| dc.date.available | 2021-12-01T18:30:37Z | en_US |
| dc.date.issued | 2021 | en_US |
| dc.description.abstract | Trapping by active sites on surfaces plays important roles in various chemical and biological processes, including catalysis, enzymatic reactions, and viral entry into host cells. However, the mechanisms of these processes remain not well understood, mostly because the existing theoretical descriptions are not fully accounting for the role of the surfaces. Here, we present a theoretical investigation on the dynamics of surface-assisted trapping by specific active sites. In our model, a diffusing particle can occasionally reversibly bind to the surface and diffuse on it before reaching the final target site. An approximate theoretical framework is developed, and its predictions are tested by Brownian dynamics computer simulations. It is found that the surface diffusion can be crucial in mediating trapping by active sites. Our theoretical predictions work reasonably well as long as the area of the active site is much smaller than the overall surface area. Potential applications of our approach are discussed. | en_US |
| dc.identifier.citation | Misiura, Mikita M., Berezhkovskii, Alexander M., Bezrukov, Sergey M., et al.. "Surface-facilitated trapping by active sites: From catalysts to viruses." <i>The Journal of Chemical Physics,</i> 155, (2021) AIP Publishing: https://doi.org/10.1063/5.0069917. | en_US |
| dc.identifier.doi | https://doi.org/10.1063/5.0069917 | en_US |
| dc.identifier.uri | https://hdl.handle.net/1911/111701 | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | AIP Publishing | en_US |
| dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
| dc.title | Surface-facilitated trapping by active sites: From catalysts to viruses | en_US |
| dc.type | Journal article | en_US |
| dc.type.dcmi | Text | en_US |
| dc.type.publication | publisher version | en_US |
Files
Original bundle
1 - 1 of 1