Obesity, Dietary Factors, Nutrition, and Breast Cancer Risk
| dc.citation.firstpage | 14 | en_US |
| dc.citation.issueNumber | 1 | en_US |
| dc.citation.journalTitle | Current Breast Cancer Reports | en_US |
| dc.citation.lastpage | 27 | en_US |
| dc.citation.volumeNumber | 10 | en_US |
| dc.contributor.author | Seiler, Annina | en_US |
| dc.contributor.author | Chen, Michelle A. | en_US |
| dc.contributor.author | Brown, Ryan L. | en_US |
| dc.contributor.author | Fagundes, Christopher P. | en_US |
| dc.date.accessioned | 2019-12-12T17:25:31Z | en_US |
| dc.date.available | 2019-12-12T17:25:31Z | en_US |
| dc.date.issued | 2018 | en_US |
| dc.description.abstract | Purpose of Review: To synthesize the critical role of obesity-associated inflammation, dietary factors, and nutrition in determining breast cancer risk. Recent Findings: Obesity-associated inflammation is strongly linked to breast cancer risk and progression, largely via two processes: inflammatory pathways and dysregulated metabolism. Cytokine production in excess adipose tissues creates a chronic inflammatory microenvironment, which favors tumor development. Lifestyle factors, including diet, have long been recognized as important determinants of breast cancer risk and mortality. Summary: Obesity increases the risk of developing breast cancer in both pre- and postmenopausal women and also negatively affects breast cancer recurrence and survival. Poor dietary habits characterized by the high intake of refined starches, sugar, and both saturated and trans-saturated fats, as well as the low intake of omega-3 fatty acids, natural antioxidants, and fiber, modulate inflammation and, thereby, appear to be linked to increased risk of breast cancer and mortality. | en_US |
| dc.identifier.citation | Seiler, Annina, Chen, Michelle A., Brown, Ryan L., et al.. "Obesity, Dietary Factors, Nutrition, and Breast Cancer Risk." <i>Current Breast Cancer Reports,</i> 10, no. 1 (2018) Springer: 14-27. https://doi.org/10.1007/s12609-018-0264-0. | en_US |
| dc.identifier.digital | nihms947648 | en_US |
| dc.identifier.doi | https://doi.org/10.1007/s12609-018-0264-0 | en_US |
| dc.identifier.uri | https://hdl.handle.net/1911/107875 | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | Springer | en_US |
| dc.rights | This is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by Springer | en_US |
| dc.subject.keyword | Obesity | en_US |
| dc.subject.keyword | Nutrition | en_US |
| dc.subject.keyword | Dietary patterns | en_US |
| dc.subject.keyword | Inflammation | en_US |
| dc.subject.keyword | Breast cancer risk | en_US |
| dc.subject.keyword | Survival | en_US |
| dc.title | Obesity, Dietary Factors, Nutrition, and Breast Cancer Risk | en_US |
| dc.type | Journal article | en_US |
| dc.type.dcmi | Text | en_US |
| dc.type.publication | post-print | en_US |
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