Localizing Interference during Naming: Convergent Neuroimaging and Neuropsychological Evidence for the Function of Broca's Area
| dc.citation.firstpage | 322 | en_US |
| dc.citation.issueNumber | 1 | en_US |
| dc.citation.journalTitle | PNAS | en_US |
| dc.citation.lastpage | 327 | en_US |
| dc.citation.volumeNumber | 106 | en_US |
| dc.contributor.author | Schnur, Tatiana T. | en_US |
| dc.contributor.author | Schwartz, Myrna F. | en_US |
| dc.contributor.author | Kimberg, Daniel Y. | en_US |
| dc.contributor.author | Hirshorn, Elizabeth | en_US |
| dc.contributor.author | Coslett, H. Branch | en_US |
| dc.contributor.author | Thompson-Schill, Sharon L. | en_US |
| dc.date.accessioned | 2013-05-09T19:52:41Z | en_US |
| dc.date.available | 2013-05-09T19:52:41Z | en_US |
| dc.date.issued | 2009 | en_US |
| dc.description.abstract | In order to produce a word, the intended word must be selected from a competing set of other words. In other domains where competition affects the selection process, the left inferior frontal gyrus (LIFG) responds to competition among incompatible representations. The aim of this study was to test whether the LIFG is necessary for resolution of competition in word production. Using a novel methodological approach applying the same rigorous analytic methods to neuropsychological data as is done with neuroimaging data, we compared brain activation patterns in normal speakers (using fMRI) with the results of lesion-deficit correlations in aphasic speakers who performed the same word production task designed to elicit competition during lexical selection. The degree of activation of the LIFG in normal speakers and damage to the LIFG in aphasic speakers was associated with performance on the production task. These convergent findings provide strong support for the hypothesis that the region of cortex commonly known as Broca's area (i.e., the posterior LIFG) serves to bias competitive interactions during language production. | en_US |
| dc.embargo.terms | none | en_US |
| dc.identifier.citation | Schnur, Tatiana T., Schwartz, Myrna F., Kimberg, Daniel Y., et al.. "Localizing Interference during Naming: Convergent Neuroimaging and Neuropsychological Evidence for the Function of Broca's Area." <i>PNAS,</i> 106, no. 1 (2009) National Academy of Science: 322-327. http://dx.doi.org/10.1073/pnas.0805874106. | en_US |
| dc.identifier.doi | http://dx.doi.org/10.1073/pnas.0805874106 | en_US |
| dc.identifier.uri | https://hdl.handle.net/1911/71109 | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | National Academy of Science | en_US |
| dc.rights | This is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by the National Academy of Science. | en_US |
| dc.subject.keyword | aphasia | en_US |
| dc.subject.keyword | language production | en_US |
| dc.subject.keyword | left inferior frontal gyrus | en_US |
| dc.subject.keyword | lexical competition | en_US |
| dc.title | Localizing Interference during Naming: Convergent Neuroimaging and Neuropsychological Evidence for the Function of Broca's Area | en_US |
| dc.type | Journal article | en_US |
| dc.type.dcmi | Text | en_US |
| dc.type.publication | post-print | en_US |