Transforming Separation Science with Single-Molecule Methods
| dc.citation.firstpage | 13622 | en_US |
| dc.citation.issueNumber | 20 | en_US |
| dc.citation.journalTitle | Analytical Chemistry | en_US |
| dc.citation.lastpage | 13629 | en_US |
| dc.citation.volumeNumber | 92 | en_US |
| dc.contributor.author | Calabrase, William | en_US |
| dc.contributor.author | Bishop, Logan D.C. | en_US |
| dc.contributor.author | Dutta, Chayan | en_US |
| dc.contributor.author | Misiura, Anastasiia | en_US |
| dc.contributor.author | Landes, Christy F. | en_US |
| dc.contributor.author | Kisley, Lydia | en_US |
| dc.contributor.org | Smalley-Curl Institute | en_US |
| dc.date.accessioned | 2020-12-16T19:47:19Z | en_US |
| dc.date.available | 2020-12-16T19:47:19Z | en_US |
| dc.date.issued | 2020 | en_US |
| dc.description.abstract | Empirical optimization of the multiscale parameters underlying chromatographic and membrane separations leads to enormous resource waste and production costs. A bottom-up approach to understand the physical phenomena underlying challenges in separations is possible with single-molecule observations of solute–stationary phase interactions. We outline single-molecule fluorescence techniques that can identify key interactions under ambient conditions. Next, we describe how studying increasingly complex samples heightens the relevance of single-molecule results to industrial applications. Finally, we illustrate how separation methods that have not been studied at the single-molecule scale can be advanced, using chiral chromatography as an example case. We hope new research directions based on a molecular approach to separations will emerge based on the ideas, technologies, and open scientific questions presented in this Perspective. | en_US |
| dc.identifier.citation | Calabrase, William, Bishop, Logan D.C., Dutta, Chayan, et al.. "Transforming Separation Science with Single-Molecule Methods." <i>Analytical Chemistry,</i> 92, no. 20 (2020) American Chemical Society: 13622-13629. https://doi.org/10.1021/acs.analchem.0c02572. | en_US |
| dc.identifier.digital | acs-analchem-0c02572 | en_US |
| dc.identifier.doi | https://doi.org/10.1021/acs.analchem.0c02572 | en_US |
| dc.identifier.uri | https://hdl.handle.net/1911/109732 | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | American Chemical Society | en_US |
| dc.rights | This is an open access article published under an ACS AuthorChoice License, which permits copying and redistribution of the article or any adaptations for non-commercial purposes. | en_US |
| dc.rights.uri | https://pubs.acs.org/page/policy/authorchoice_termsofuse.html | en_US |
| dc.title | Transforming Separation Science with Single-Molecule Methods | en_US |
| dc.type | Journal article | en_US |
| dc.type.dcmi | Text | en_US |
| dc.type.publication | publisher version | en_US |
Files
Original bundle
1 - 1 of 1