Finite population size effects in quasispecies models with single-peak fitness landscape

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dc.citation.firstpage18001en_US
dc.citation.journalTitleEPLen_US
dc.citation.volumeNumber98en_US
dc.contributor.authorSaakian, David B.en_US
dc.contributor.authorDeem, Michael W.en_US
dc.contributor.authorHu, Chin-Kunen_US
dc.date.accessioned2013-03-13T19:59:09Zen_US
dc.date.available2014-03-19T05:10:03Zen_US
dc.date.issued2012-04en_US
dc.description.abstractWe consider finite population size effects for Crow-Kimura and Eigen quasispecies models with single-peak fitness landscape. We formulate accurately the iteration procedure for the finite population models, then derive the Hamilton-Jacobi equation (HJE) to describe the dynamic of the probability distribution. The steady-state solution of HJE gives the variance of the mean fitness. Our results are useful for understanding the population sizes of viruses in which the infinite population models can give reliable results for biological evolution problems.en_US
dc.embargo.terms1 yearen_US
dc.identifier.citationSaakian, David B., Deem, Michael W. and Hu, Chin-Kun. "Finite population size effects in quasispecies models with single-peak fitness landscape." <i>EPL,</i> 98, (2012) IOP Publishing: 18001. http://dx.doi.org/10.1209/0295-5075/98/18001.en_US
dc.identifier.doihttp://dx.doi.org/10.1209/0295-5075/98/18001en_US
dc.identifier.urihttps://hdl.handle.net/1911/70576en_US
dc.language.isoengen_US
dc.publisherIOP Publishingen_US
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.en_US
dc.titleFinite population size effects in quasispecies models with single-peak fitness landscapeen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpublisher versionen_US
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