We use the ab initio Bethe ansatz dynamics to predict the dissociation of one-dimensional cold-atom breathers that are created by a quench from a fundamental soliton. We find that the dissociation is a robust quantum many-body effect, while in the mean-field (MF) limit the dissociation is forbidden by the integrability of the underlying nonlinear Schrödinger equation. The analysis demonstrates the possibility to observe quantum many-body effects without leaving the MF range of experimental parameters. We find that the dissociation time is of the order of a few seconds for a typical atomic-soliton setting.