Improving the efficiency of molecular replacement by utilizing a new iterative transform phasing algorithm

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dc.citation.firstpage539
dc.citation.journalTitleActa Crystallographica
dc.citation.lastpage547
dc.citation.volumeNumberA72
dc.contributor.authorHe, Hongxing
dc.contributor.authorFang, Hengrui
dc.contributor.authorMiller, Mitchell D.
dc.contributor.authorPhillips, George N.Jr.
dc.contributor.authorSu, Wu-Pei
dc.date.accessioned2016-11-10T22:23:40Z
dc.date.available2016-11-10T22:23:40Z
dc.date.issued2016
dc.description.abstractAn iterative transform method proposed previously for direct phasing of high-solvent-content protein crystals is employed for enhancing the molecular-replacement (MR) algorithm in protein crystallography. Target structures that are resistant to conventional MR due to insufficient similarity between the template and target structures might be tractable with this modified phasing method. Trial calculations involving three different structures are described to test and illustrate the methodology. The relationship of the approach toﾠPHENIX Phaser-MRﾠandﾠMR-Rosettaﾠis discussed.
dc.identifier.citationHe, Hongxing, Fang, Hengrui, Miller, Mitchell D., et al.. "Improving the efficiency of molecular replacement by utilizing a new iterative transform phasing algorithm." <i>Acta Crystallographica,</i> A72, (2016) International Union of Crystallography: 539-547. http://dx.doi.org/10.1107/S2053273316010731.
dc.identifier.doihttp://dx.doi.org/10.1107/S2053273316010731
dc.identifier.urihttps://hdl.handle.net/1911/92704
dc.language.isoeng
dc.publisherInternational Union of Crystallography
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
dc.subject.keywordmolecular replacement
dc.subject.keywordhybrid inputﾖoutput algorithm
dc.subject.keywordab initio phasing
dc.subject.keywordprotein crystallography
dc.titleImproving the efficiency of molecular replacement by utilizing a new iterative transform phasing algorithm
dc.typeJournal article
dc.type.dcmiText
dc.type.publicationpublisher version
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