Exercise, inflammation, and fatigue in cancer survivors

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dc.citation.firstpage82
dc.citation.journalTitleExercise Immunology Review
dc.citation.lastpage93
dc.citation.volumeNumber22
dc.contributor.authorLaVoy, Emily C.P.
dc.contributor.authorFagundes, Christopher P.
dc.contributor.authorDantzer, Robert
dc.date.accessioned2016-10-21T18:32:23Z
dc.date.available2016-10-21T18:32:23Z
dc.date.issued2016
dc.description.abstractCancer-related fatigue significantly disrupts normal functioning and quality of life for a substantial portion of cancer survivors, and may persist for years following cancer treatment. While the causes of persistent fatigue among cancer survivors are not yet fully understood, accumulating evidence suggests that several pathways, including chronic inflammation, autonomic imbalance, HPA-axis dysfunction, and/or mitochondrial damage, could contribute towards the disruption of normal neuronal function and result in the symptom of cancer-related fatigue. Exercise training interventions have been shown to be some of the more successful treatment options to address cancer-related fatigue. In this review, we discuss the literature regarding the causes of persistent fatigue in cancer survivors and the mechanisms by which exercise may relieve this symptom. There is still much work to be done until the prescription of exercise becomes standard practice for cancer survivors. With improvements in the quality of studies, evidenced-based exercise interventions will allow exercise scientists and oncologists to work together to treat cancer-related fatigue.
dc.identifier.citationLaVoy, Emily C.P., Fagundes, Christopher P. and Dantzer, Robert. "Exercise, inflammation, and fatigue in cancer survivors." <i>Exercise Immunology Review,</i> 22, (2016) International Society of Exercise and Immunology: 82-93. <a href="https://hdl.handle.net/1911/91987">https://hdl.handle.net/1911/91987</a>.
dc.identifier.urihttps://hdl.handle.net/1911/91987
dc.language.isoeng
dc.publisherInternational Society of Exercise and Immunology
dc.rightsThis is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by International Society ofﾠExerciseﾠandﾠImmunology.
dc.titleExercise, inflammation, and fatigue in cancer survivors
dc.typeJournal article
dc.type.dcmiText
dc.type.publicationpost-print
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