Enabling accurate and early detection of recently emerged SARS-CoV-2 variants of concern in wastewater

dc.citation.articleNumber2834en_US
dc.citation.journalTitleNature Communicationsen_US
dc.citation.volumeNumber14en_US
dc.contributor.authorSapoval, Nicolaeen_US
dc.contributor.authorLiu, Yunxien_US
dc.contributor.authorLou, Esther G.en_US
dc.contributor.authorHopkins, Lorenen_US
dc.contributor.authorEnsor, Katherine B.en_US
dc.contributor.authorSchneider, Rebeccaen_US
dc.contributor.authorStadler, Lauren B.en_US
dc.contributor.authorTreangen, Todd J.en_US
dc.date.accessioned2023-07-21T16:14:05Zen_US
dc.date.available2023-07-21T16:14:05Zen_US
dc.date.issued2023en_US
dc.description.abstractAs clinical testing declines, wastewater monitoring can provide crucial surveillance on the emergence of SARS-CoV-2 variant of concerns (VoCs) in communities. In this paper we present QuaID, a novel bioinformatics tool for VoC detection based on quasi-unique mutations. The benefits of QuaID are three-fold: (i) provides up to 3-week earlier VoC detection, (ii) accurate VoC detection (>95% precision on simulated benchmarks), and (iii) leverages all mutational signatures (including insertions & deletions).en_US
dc.identifier.citationSapoval, Nicolae, Liu, Yunxi, Lou, Esther G., et al.. "Enabling accurate and early detection of recently emerged SARS-CoV-2 variants of concern in wastewater." <i>Nature Communications,</i> 14, (2023) Springer Nature: https://doi.org/10.1038/s41467-023-38184-3.en_US
dc.identifier.digitals41467-023-38184-3en_US
dc.identifier.doihttps://doi.org/10.1038/s41467-023-38184-3en_US
dc.identifier.urihttps://hdl.handle.net/1911/115014en_US
dc.language.isoengen_US
dc.publisherSpringer Natureen_US
dc.rightsExcept where otherwise noted, this work is licensed under a Creative Commons Attribution (CC BY) license.  Permission to reuse, publish, or reproduce the work beyond the terms of the license or beyond the bounds of Fair Use or other exemptions to copyright law must be obtained from the copyright holder.en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en_US
dc.titleEnabling accurate and early detection of recently emerged SARS-CoV-2 variants of concern in wastewateren_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpublisher versionen_US
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