Behavioral Symptoms after Breast Cancer Treatment: A Biobehavioral Approach

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dc.citation.firstpage280en_US
dc.citation.journalTitleJournal of Personalized Medicineen_US
dc.citation.lastpage295en_US
dc.citation.volumeNumber5en_US
dc.contributor.authorFagundes, Christopheren_US
dc.contributor.authorLeRoy, Angieen_US
dc.contributor.authorKaruga, Maryanneen_US
dc.date.accessioned2016-10-21T17:01:00Zen_US
dc.date.available2016-10-21T17:01:00Zen_US
dc.date.issued2015en_US
dc.description.abstractBeing diagnosed and treated for breast cancer is emotionally and physically challenging. Breast cancer is the most commonly diagnosed cancer and the second leading cause of death for women in the United States. Accordingly, women with a breast cancer history are the largest group of female cancer survivors. Psychological stress substantially augments adverse autonomic, endocrine, and immune discharge, including enhanced production of proinflammatory cytokines. Importantly, inflammation is a key biological mechanism underlying the symptom cluster of pain, depression, fatigue, and sleep disturbances; there is also good evidence that inflammation contributes to breast cancer recurrence. Stress may exert direct effects on psychological and physiological risk processes. In this review, we take a biobehavioral approach to understanding predictors and mechanisms underlying somatic symptoms in breast cancer survivors.en_US
dc.identifier.citationFagundes, Christopher, LeRoy, Angie and Karuga, Maryanne. "Behavioral Symptoms after Breast Cancer Treatment: A Biobehavioral Approach." <i>Journal of Personalized Medicine,</i> 5, (2015) MDPI: 280-295. http://dx.doi.org/10.3390/jpm5030280.en_US
dc.identifier.doihttp://dx.doi.org/10.3390/jpm5030280en_US
dc.identifier.urihttps://hdl.handle.net/1911/91983en_US
dc.language.isoengen_US
dc.publisherMDPIen_US
dc.rightsThis article is an open access article distributed under the terms and conditions of the Creative Commons Attribution licenseen_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_US
dc.subject.keywordSESen_US
dc.subject.keywordbreast cancer survivorsen_US
dc.subject.keywordchronic stressorsen_US
dc.subject.keyworddepressionen_US
dc.subject.keywordfatigueen_US
dc.subject.keywordinflammationen_US
dc.subject.keywordproinflammatory cytokine productionen_US
dc.subject.keywordrecurrenceen_US
dc.titleBehavioral Symptoms after Breast Cancer Treatment: A Biobehavioral Approachen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpublisher versionen_US
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