Behavioral Symptoms after Breast Cancer Treatment: A Biobehavioral Approach

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dc.citation.firstpage280
dc.citation.journalTitleJournal of Personalized Medicine
dc.citation.lastpage295
dc.citation.volumeNumber5
dc.contributor.authorFagundes, Christopher
dc.contributor.authorLeRoy, Angie
dc.contributor.authorKaruga, Maryanne
dc.date.accessioned2016-10-21T17:01:00Z
dc.date.available2016-10-21T17:01:00Z
dc.date.issued2015
dc.description.abstractBeing diagnosed and treated for breast cancer is emotionally and physically challenging. Breast cancer is the most commonly diagnosed cancer and the second leading cause of death for women in the United States. Accordingly, women with a breast cancer history are the largest group of female cancer survivors. Psychological stress substantially augments adverse autonomic, endocrine, and immune discharge, including enhanced production of proinflammatory cytokines. Importantly, inflammation is a key biological mechanism underlying the symptom cluster of pain, depression, fatigue, and sleep disturbances; there is also good evidence that inflammation contributes to breast cancer recurrence. Stress may exert direct effects on psychological and physiological risk processes. In this review, we take a biobehavioral approach to understanding predictors and mechanisms underlying somatic symptoms in breast cancer survivors.
dc.identifier.citationFagundes, Christopher, LeRoy, Angie and Karuga, Maryanne. "Behavioral Symptoms after Breast Cancer Treatment: A Biobehavioral Approach." <i>Journal of Personalized Medicine,</i> 5, (2015) MDPI: 280-295. http://dx.doi.org/10.3390/jpm5030280.
dc.identifier.doihttp://dx.doi.org/10.3390/jpm5030280
dc.identifier.urihttps://hdl.handle.net/1911/91983
dc.language.isoeng
dc.publisherMDPI
dc.rightsThis article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.keywordSES
dc.subject.keywordbreast cancer survivors
dc.subject.keywordchronic stressors
dc.subject.keyworddepression
dc.subject.keywordfatigue
dc.subject.keywordinflammation
dc.subject.keywordproinflammatory cytokine production
dc.subject.keywordrecurrence
dc.titleBehavioral Symptoms after Breast Cancer Treatment: A Biobehavioral Approach
dc.typeJournal article
dc.type.dcmiText
dc.type.publicationpublisher version
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