We develop the basic theory of ergodic Schrödinger operators, which is well known for ergodic probability measures, in the case of a base dynamics on an infinite measure space. This includes the almost sure constancy of the spectrum and the spectral type, the definition and discussion of the density of states measure and the Lyapunov exponent, as well as a version of the Pastur–Ishii theorem. We also give some counterexamples that demonstrate that some results do not extend from the finite measure case to the infinite measure case. These examples are based on some constructions in infinite ergodic theory that may be of independent interest.