Desacetoxytubulysin H and analogs thereof

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dc.contributor.assigneeRice University
dc.contributor.publisherUnited States Patent and Trademark Office
dc.creatorNicolaou, Kyriacos C.
dc.creatorVourloumis, Dionisios
dc.creatorYin, Jun
dc.creatorErande, Rohan
dc.creatorMandal, Debashis
dc.creatorKlahn, Phillipp
dc.date.accessioned2021-03-02T21:04:40Z
dc.date.available2021-03-02T21:04:40Z
dc.date.filed2016-02-25
dc.date.issued2020-10-20
dc.description.abstract"In one aspect, the present disclosure provides tubulysin analogs of the formula (I) wherein R1, R2, R3, R4, X1, X2, X3, and A1 are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. "
dc.digitization.specificationsThis patent information was downloaded from the US Patent and Trademark website (http://www.uspto.gov/) as image-PDFs. The PDFs were OCRed for access purposes
dc.format.extent259
dc.identifier.citationNicolaou, Kyriacos C., Vourloumis, Dionisios, Yin, Jun, Erande, Rohan, Mandal, Debashis and Klahn, Phillipp, "Desacetoxytubulysin H and analogs thereof." Patent US10808007B2. issued 2020-10-20. Retrieved from <a href="https://hdl.handle.net/1911/110116">https://hdl.handle.net/1911/110116</a>.
dc.identifier.patentIDUS10808007B2
dc.identifier.urihttps://hdl.handle.net/1911/110116
dc.language.isoeng
dc.titleDesacetoxytubulysin H and analogs thereof
dc.typeUtility patent
dc.type.dcmiText
dc.type.genrepatents
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