Desacetoxytubulysin H and analogs thereof

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dc.contributor.assigneeRice Universityen_US
dc.contributor.publisherUnited States Patent and Trademark Officeen_US
dc.creatorNicolaou, Kyriacos C.en_US
dc.creatorVourloumis, Dionisiosen_US
dc.creatorYin, Junen_US
dc.creatorErande, Rohanen_US
dc.creatorMandal, Debashisen_US
dc.creatorKlahn, Phillippen_US
dc.date.accessioned2021-03-02T21:04:40Zen_US
dc.date.available2021-03-02T21:04:40Zen_US
dc.date.filed2016-02-25en_US
dc.date.issued2020-10-20en_US
dc.description.abstract"In one aspect, the present disclosure provides tubulysin analogs of the formula (I) wherein R1, R2, R3, R4, X1, X2, X3, and A1 are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. "en_US
dc.digitization.specificationsThis patent information was downloaded from the US Patent and Trademark website (http://www.uspto.gov/) as image-PDFs. The PDFs were OCRed for access purposesen_US
dc.format.extent259en_US
dc.identifier.citationNicolaou, Kyriacos C., Vourloumis, Dionisios, Yin, Jun, Erande, Rohan, Mandal, Debashis and Klahn, Phillipp, "Desacetoxytubulysin H and analogs thereof." Patent US10808007B2. issued 2020-10-20. Retrieved from <a href="https://hdl.handle.net/1911/110116">https://hdl.handle.net/1911/110116</a>.en_US
dc.identifier.patentIDUS10808007B2en_US
dc.identifier.urihttps://hdl.handle.net/1911/110116en_US
dc.language.isoengen_US
dc.titleDesacetoxytubulysin H and analogs thereofen_US
dc.typeUtility patenten_US
dc.type.dcmiTexten_US
dc.type.genrepatentsen_US
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