The Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections

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dc.citation.articleNumbere0004944en_US
dc.citation.issueNumber9en_US
dc.citation.journalTitlePLoS Neglected Tropical Diseasesen_US
dc.citation.volumeNumber10en_US
dc.contributor.authorBriggs, Neimaen_US
dc.contributor.authorWeatherhead, Jillen_US
dc.contributor.authorSastry, K. Jagannadhaen_US
dc.contributor.authorHotez, Peter J.en_US
dc.date.accessioned2017-05-19T19:09:39Zen_US
dc.date.available2017-05-19T19:09:39Zen_US
dc.date.issued2016en_US
dc.description.abstractCurrent iterations of the hygiene hypothesis suggest an adaptive role for helminth parasites in shaping the proper maturation of the immune system. However, aspects of this hypothesis are based on assumptions that may not fully account for realities about human helminth infections. Such realities include evidence of causal associations between helminth infections and asthma or inflammatory bowel disease as well as the fact that helminth infections remain widespread in the United States, especially among populations at greatest risk for inflammatory and autoimmune diseases.en_US
dc.identifier.citationBriggs, Neima, Weatherhead, Jill, Sastry, K. Jagannadha, et al.. "The Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections." <i>PLoS Neglected Tropical Diseases,</i> 10, no. 9 (2016) Public Library of Science: https://doi.org/10.1371/journal.pntd.0004944.en_US
dc.identifier.doihttps://doi.org/10.1371/journal.pntd.0004944en_US
dc.identifier.urihttps://hdl.handle.net/1911/94290en_US
dc.language.isoengen_US
dc.publisherPublic Library of Scienceen_US
dc.rightsThis is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en_US
dc.titleThe Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infectionsen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpublisher versionen_US
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