Transcriptional responses to direct and indirect TGFB1 stimulation in cancerous and noncancerous mammary epithelial cells

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dc.citation.articleNumber522en_US
dc.citation.issueNumber1en_US
dc.citation.journalTitleCell Communication and Signalingen_US
dc.citation.volumeNumber22en_US
dc.contributor.authorJanus, Patryken_US
dc.contributor.authorKuś, Pawełen_US
dc.contributor.authorJaksik, Romanen_US
dc.contributor.authorVydra, Nataliaen_US
dc.contributor.authorToma-Jonik, Agnieszkaen_US
dc.contributor.authorGramatyka, Michalinaen_US
dc.contributor.authorKurpas, Monikaen_US
dc.contributor.authorKimmel, Mareken_US
dc.contributor.authorWidłak, Wiesławaen_US
dc.date.accessioned2024-11-20T15:52:05Zen_US
dc.date.available2024-11-20T15:52:05Zen_US
dc.date.issued2024en_US
dc.description.abstractTransforming growth factor beta (TGFβ) is important for the morphogenesis and secretory function of the mammary gland. It is one of the main activators of the epithelial–mesenchymal transition (EMT), a process important for tissue remodeling and regeneration. It also provides cells with the plasticity to form metastases during tumor progression. Noncancerous and cancer cells respond differently to TGFβ. However, knowledge of the cellular signaling cascades triggered by TGFβ in various cell types is still limited.en_US
dc.identifier.citationJanus, P., Kuś, P., Jaksik, R., Vydra, N., Toma-Jonik, A., Gramatyka, M., Kurpas, M., Kimmel, M., & Widłak, W. (2024). Transcriptional responses to direct and indirect TGFB1 stimulation in cancerous and noncancerous mammary epithelial cells. Cell Communication and Signaling, 22(1), 522. https://doi.org/10.1186/s12964-024-01821-5en_US
dc.identifier.digitals12964-024-01821-5en_US
dc.identifier.doihttps://doi.org/10.1186/s12964-024-01821-5en_US
dc.identifier.urihttps://hdl.handle.net/1911/118062en_US
dc.language.isoengen_US
dc.publisherSpringer Natureen_US
dc.rightsExcept where otherwise noted, this work is licensed under a Creative Commons Attribution (CC BY) license. Permission to reuse, publish, or reproduce the work beyond the terms of the license or beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en_US
dc.subject.keywordBystander effecten_US
dc.subject.keywordCell deathen_US
dc.subject.keywordEMTen_US
dc.subject.keywordCell cycleen_US
dc.subject.keywordEstrogen signalingen_US
dc.subject.keywordMammary epithelial cellsen_US
dc.subject.keywordMCF10Aen_US
dc.subject.keywordMCF7en_US
dc.subject.keywordTGFβ signalingen_US
dc.titleTranscriptional responses to direct and indirect TGFB1 stimulation in cancerous and noncancerous mammary epithelial cellsen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpublisher versionen_US
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