All-plastic, miniature, digital fluorescence microscope for three part white blood cell differential measurements at the point of care

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dc.citation.firstpage4433
dc.citation.issueNumber11
dc.citation.journalTitleBiomedical Optics Express
dc.citation.lastpage4446
dc.citation.volumeNumber6
dc.contributor.authorForcucci, Alessandra
dc.contributor.authorPawlowski, Michal E.
dc.contributor.authorMajors, Catherine
dc.contributor.authorRichards-Kortum, Rebecca
dc.contributor.authorTkaczyk, Tomasz S.
dc.date.accessioned2016-01-15T19:47:52Z
dc.date.available2016-01-15T19:47:52Z
dc.date.issued2015
dc.description.abstractThree-part differential white blood cell counts are used for disease diagnosis and monitoring at the point-of-care. A low-cost, miniature achromatic microscope was fabricated for identification of lymphocytes, monocytes, and granulocytes in samples of whole blood stained with acridine orange. The microscope was manufactured using rapid prototyping techniques of diamond turning and 3D printing and is intended for use at the point-of-care in low-resource settings. The custom-designed microscope requires no manual adjustment between samples and was successfully able to classify three white blood cell types (lymphocytes, granulocytes, and monocytes) using samples of peripheral whole blood stained with acridine orange.
dc.identifier.citationForcucci, Alessandra, Pawlowski, Michal E., Majors, Catherine, et al.. "All-plastic, miniature, digital fluorescence microscope for three part white blood cell differential measurements at the point of care." <i>Biomedical Optics Express,</i> 6, no. 11 (2015) The Optical Society: 4433-4446. http://dx.doi.org/10.1364/BOE.6.004433.
dc.identifier.doihttp://dx.doi.org/10.1364/BOE.6.004433
dc.identifier.urihttps://hdl.handle.net/1911/87854
dc.language.isoeng
dc.publisherThe Optical Society
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
dc.titleAll-plastic, miniature, digital fluorescence microscope for three part white blood cell differential measurements at the point of care
dc.typeJournal article
dc.type.dcmiText
dc.type.publicationpublisher version
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