All-plastic, miniature, digital fluorescence microscope for three part white blood cell differential measurements at the point of care

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dc.citation.firstpage4433en_US
dc.citation.issueNumber11en_US
dc.citation.journalTitleBiomedical Optics Expressen_US
dc.citation.lastpage4446en_US
dc.citation.volumeNumber6en_US
dc.contributor.authorForcucci, Alessandraen_US
dc.contributor.authorPawlowski, Michal E.en_US
dc.contributor.authorMajors, Catherineen_US
dc.contributor.authorRichards-Kortum, Rebeccaen_US
dc.contributor.authorTkaczyk, Tomasz S.en_US
dc.date.accessioned2016-01-15T19:47:52Zen_US
dc.date.available2016-01-15T19:47:52Zen_US
dc.date.issued2015en_US
dc.description.abstractThree-part differential white blood cell counts are used for disease diagnosis and monitoring at the point-of-care. A low-cost, miniature achromatic microscope was fabricated for identification of lymphocytes, monocytes, and granulocytes in samples of whole blood stained with acridine orange. The microscope was manufactured using rapid prototyping techniques of diamond turning and 3D printing and is intended for use at the point-of-care in low-resource settings. The custom-designed microscope requires no manual adjustment between samples and was successfully able to classify three white blood cell types (lymphocytes, granulocytes, and monocytes) using samples of peripheral whole blood stained with acridine orange.en_US
dc.identifier.citationForcucci, Alessandra, Pawlowski, Michal E., Majors, Catherine, et al.. "All-plastic, miniature, digital fluorescence microscope for three part white blood cell differential measurements at the point of care." <i>Biomedical Optics Express,</i> 6, no. 11 (2015) The Optical Society: 4433-4446. http://dx.doi.org/10.1364/BOE.6.004433.en_US
dc.identifier.doihttp://dx.doi.org/10.1364/BOE.6.004433en_US
dc.identifier.urihttps://hdl.handle.net/1911/87854en_US
dc.language.isoengen_US
dc.publisherThe Optical Societyen_US
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.en_US
dc.titleAll-plastic, miniature, digital fluorescence microscope for three part white blood cell differential measurements at the point of careen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpublisher versionen_US
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