THERAPEUTIC COMPOSITIONS AND METHODS FOR DELIVERY OF ACTIVE AGENTS CLEAVABLY LINKED TO NANOPARTICLES

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dc.contributor.assigneeRice Universityeng
dc.contributor.publisherUnited States Patent and Trademark Officeeng
dc.creatorZubarev, Eugene
dc.creatorGibson, Jacob
dc.date.accessioned2015-10-27T14:01:01Z
dc.date.available2015-10-27T14:01:01Z
dc.date.filed2010-12-09
dc.date.issued2015-09-22
dc.description.abstractVarious embodiments of the present invention pertain to therapeutic compositions that comprise: (1) an active agent (e.g., paclitaxel); and (2) a nanoparticle (e.g., gold nanoparticle). In such embodiments, the active agent is covalently linked to the nanoparticle through a cleavable linker (e.g., a linker containing a hydrazone species). Other embodiments of the present invention pertain to methods of treating a condition in a subject by administering the above-described therapeutic compositions to the subject.eng
dc.digitization.specificationsThis patent information was downloaded from the US Patent and Trademark website (http://www.uspto.gov/) as image-PDFs. The PDFs were OCRed for access purposeseng
dc.format.extent11eng
dc.identifier.citationZubarev, Eugene and Gibson, Jacob, "THERAPEUTIC COMPOSITIONS AND METHODS FOR DELIVERY OF ACTIVE AGENTS CLEAVABLY LINKED TO NANOPARTICLES." Patent US9138418B2. issued 2015-09-22. Retrieved from <a href="https://hdl.handle.net/1911/81931">https://hdl.handle.net/1911/81931</a>.
dc.identifier.patentIDUS9138418B2eng
dc.identifier.urihttps://hdl.handle.net/1911/81931
dc.language.isoengeng
dc.titleTHERAPEUTIC COMPOSITIONS AND METHODS FOR DELIVERY OF ACTIVE AGENTS CLEAVABLY LINKED TO NANOPARTICLESeng
dc.typeUtility patenteng
dc.type.dcmiTexteng
dc.type.genrepatentseng
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