A bi-functional nano-composite coating has been created on a porous Nomex fabric support as a trap for aspirated virus contaminated water. Nomex fabric was successively dip-coated in solutions containing cysteic acid functionalized alumina (alumoxane) nanoparticles and cysteic acid functionalized iron oxide (ferroxane) nanoparticles to form a nanoparticle coated Nomex (NPN) fabric. From SEM and EDX the nanoparticle coating of the Nomex fibers is uniform, continuous, and conformal. The NPN was used as a filter for aspirated bacteriophage MS2 viruses using end-on filtration. All measurements were repeated to give statistical reliability. The NPN fabrics show a large decrease as compared to Nomex alone or alumoxane coated Nomex . An increase in the ferroxane content results in an equivalent increase in virus retention. This suggests that it is the ferroxane that has an active role in deactivating and/or binding the virus. Heating the NPN to 160 C results in the loss of cysteic acid functional groups (without loss of the iron nanoparticleﾒs core structure) and the resulting fabric behaves similar to that of untreated Nomex , showing that the surface functionalization of the nanoparticles is vital for the surface collapse of aspirated water droplets and the absorption and immobilization of the MS2 viruses. Thus, for virus immobilization, it is not sufficient to have iron oxide nanoparticles per se, but the surface functionality of a nanoparticle is vitally important in ensuring efficacy.