A gain-of-function mutation in IAA16 confers reduced responses to auxin and abscisic acid and impedes plant growth and fertility

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dc.citation.firstpage359
dc.citation.journalTitlePlant Molecular Biology
dc.citation.lastpage373
dc.citation.volumeNumber79
dc.contributor.authorRinaldi, Mauro A.
dc.contributor.authorLiu, James
dc.contributor.authorEnders, Tara A.
dc.contributor.authorBartel, Bonnie
dc.contributor.authorStrader, Lucia C.
dc.date.accessioned2015-01-06T15:49:13Z
dc.date.available2015-01-06T15:49:13Z
dc.date.issued2012
dc.description.abstractAuxin regulates many aspects of plant development, in part, through degradation of the Aux/IAA family of transcriptional repressors. Consequently, stabilizing mutations in several Aux/IAA proteins confer reduced auxin responsiveness. However, of the 29 apparent Aux/IAA proteins in Arabidopsis thaliana, fewer than half have roles established through mutant analysis. We identified iaa16-1, a dominant gain-of-function mutation in IAA16 (At3g04730), in a novel screen for reduced root responsiveness to abscisic acid. The iaa16-1 mutation also confers dramatically reduced auxin responses in a variety of assays, markedly restricts growth of adult plants, and abolishes fertility when homozygous. We compared iaa16-1 phenotypes with those of dominant mutants defective in the closely related IAA7/AXR2, IAA14/SLR, and IAA17/AXR3, along with the more distantly related IAA28, and found overlapping but distinct patterns of developmental defects. The identification and characterization of iaa16-1 provides a fuller understanding of the IAA7/IAA14/IAA16/IAA17 clade of Aux/IAA proteins and the diverse roles of these repressors in hormone response and plant development.
dc.identifier.citationRinaldi, Mauro A., Liu, James, Enders, Tara A., et al.. "A gain-of-function mutation in IAA16 confers reduced responses to auxin and abscisic acid and impedes plant growth and fertility." <i>Plant Molecular Biology,</i> 79, no. 4-5 (2012) Springer: 359-373. http://dx.doi.org/10.1007/s11103-012-9917-y.
dc.identifier.doihttp://dx.doi.org/10.1007/s11103-012-9917-y
dc.identifier.urihttps://hdl.handle.net/1911/78887
dc.language.isoeng
dc.publisherSpringer
dc.rightsThis is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by Springer.
dc.subject.keywordauxin signaling
dc.subject.keywordabscisic acid
dc.subject.keywordAux/IAA gain of function
dc.subject.keywordIAA16
dc.titleA gain-of-function mutation in IAA16 confers reduced responses to auxin and abscisic acid and impedes plant growth and fertility
dc.typeJournal article
dc.type.dcmiTexten_US
dc.type.publicationpost-print
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