Designing synthetic biological circuits using optimality and nonequilibrium thermodynamics

Simple item page
dc.contributor.assigneeRice Universityen_US
dc.contributor.assigneeGeneral Hospital Corporationen_US
dc.contributor.publisherUnited States Patent and Trademark Officeen_US
dc.creatorNagrath, Deepaken_US
dc.creatorAvila-Elchiver, Marcoen_US
dc.creatorYarmush, Martinen_US
dc.date.accessioned2015-05-04T19:06:04Z
dc.date.available2015-05-04T19:06:04Z
dc.date.filed2011-09-30en_US
dc.date.issued2013-08-06en_US
dc.description.abstractIn general, the invention relates to a method for designing a biological circuit. The method includes obtaining a target circuit objective for the biological circuit, determining an objective function corresponding to the target circuit objective, obtaining a number of nodes for the biological circuit, obtaining a set of possible circuit subgraphs using the number of nodes, obtaining a specific dissipation energy (SDE) for each one of the set of possible circuit subgraphs by optimizing the objective function, selecting at least one circuit subgraph from the set of possible circuit subgraphs with the lowest SDE, and designing the biological circuit using the at least one selected one circuit subgraph.en_US
dc.digitization.specificationsThis patent information was downloaded from the US Patent and Trademark website (http://www.uspto.gov/) as image-PDFs. The PDFs were OCRed for access purposes.en_US
dc.format.extent42 ppen_US
dc.identifier.citationNagrath, Deepak, Avila-Elchiver, Marco and Yarmush, Martin, "Designing synthetic biological circuits using optimality and nonequilibrium thermodynamics." Patent US8504948B2. issued 2013-08-06. Retrieved from https://hdl.handle.net/1911/80131.
dc.identifier.patentIDUS8504948B2en_US
dc.identifier.urihttps://hdl.handle.net/1911/80131
dc.language.isoengen_US
dc.titleDesigning synthetic biological circuits using optimality and nonequilibrium thermodynamicsen_US
dc.typeUtility patenten_US
dc.type.dcmiTexten_US
dc.type.genrepatentsen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
US8504948B2.pdf
Size:
4.13 MB
Format:
Adobe Portable Document Format
Download
Collections
Rice Patents