Structure and assembly of the influenza A virus ribonucleoprotein complex

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dc.citation.firstpage1206
dc.citation.issueNumber8
dc.citation.journalTitleFEBS Letters
dc.citation.lastpage1214
dc.citation.volumeNumber587
dc.contributor.authorZheng, Wenj
dc.contributor.authorTao, Yizhi Jane
dc.date.accessioned2014-10-06T17:18:00Z
dc.date.available2014-10-06T17:18:00Z
dc.date.issued2013
dc.description.abstractThe genome of influenza A viruses consists of eight segments of single-stranded, negative-sense RNA that are encapsidated as individual rod-shaped ribonucleoprotein complexes (RNPs). Each RNP contains a viral RNA, a viral polymerase and multiple copies of the viral nucleoprotein (NP). Influenza A virus RNPs play important roles during virus infection by directing viral RNA replication and transcription, intracellular transport of the viral RNA, gene reassortment as well as viral genome packaging into progeny particles. As a unique genomic entity, the influenza A virus RNP has been extensively studied since the 1960s. Recently, exciting progress has been made in studying the RNP structure and its assembly, leading to a better understanding of the structural basis of various RNP functions.
dc.identifier.citationZheng, Wenj and Tao, Yizhi Jane. "Structure and assembly of the influenza A virus ribonucleoprotein complex." <i>FEBS Letters,</i> 587, no. 8 (2013) Elsevier: 1206-1214. http://dx.doi.org/10.1016/j.febslet.2013.02.048.
dc.identifier.doihttp://dx.doi.org/10.1016/j.febslet.2013.02.048
dc.identifier.urihttps://hdl.handle.net/1911/77394
dc.language.isoeng
dc.publisherElsevier
dc.rightsThis is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/3.0/
dc.subject.keywordInfluenza A virus
dc.subject.keywordRibonucleoprotein complex
dc.subject.keywordRNP
dc.subject.keywordnucleoprotein
dc.subject.keywordNP
dc.subject.keywordstructure
dc.subject.keywordassembly
dc.titleStructure and assembly of the influenza A virus ribonucleoprotein complex
dc.typeJournal article
dc.type.dcmiText
dc.type.publicationpublisher version
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