Temperature-sensitive polymer/nanoshell composites for photothermally modulated drug delivery

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dc.contributor.assigneeRice Universityen_US
dc.contributor.publisherUnited States Patent and Trademark Officeen_US
dc.creatorWest, Jennifer L.en_US
dc.creatorSershen, Scott R.en_US
dc.creatorHalas, Nancy J.en_US
dc.creatorOldenburg, Steven J.en_US
dc.creatorAveritt, Richard D.en_US
dc.date.accessioned2015-05-04T19:05:31Z
dc.date.available2015-05-04T19:05:31Z
dc.date.filed2000-07-14en_US
dc.date.issued2002-08-06en_US
dc.description.abstractA thermally sensitive polymer-particle composite that absorbs electromagnetic radiation, and uses the absorbed energy to trigger the delivery of a chemical is disclosed. Metal nanoshells are nanoparticulate materials that are suitable for use in the present composites and can be made according to a process that includes optically tuning or tailoring their maximum optical absorption to any desired wavelength primarily by altering the ratio of the core diameter to the shell thickness. Preferred nanoshells are selected that strongly absorb light in the near-infrared and thus produce heat. These nanoshells are combined with a temperature-sensitive material to provide an implantable or injectable material for modulated drug delivery via external exposure to near-IR light. This invention provides a means to improve the quality of life for persons requiring multiple injections of a drug, such as diabetes mellitus patients.en_US
dc.digitization.specificationsThis patent information was downloaded from the US Patent and Trademark website (http://www.uspto.gov/) as image-PDFs. The PDFs were OCRed for access purposes.en_US
dc.format.extent17 ppen_US
dc.identifier.citationWest, Jennifer L., Sershen, Scott R., Halas, Nancy J., Oldenburg, Steven J. and Averitt, Richard D., "Temperature-sensitive polymer/nanoshell composites for photothermally modulated drug delivery." Patent US6428811B1. issued 2002-08-06. Retrieved from https://hdl.handle.net/1911/79850.
dc.identifier.patentIDUS6428811B1en_US
dc.identifier.urihttps://hdl.handle.net/1911/79850
dc.language.isoengen_US
dc.titleTemperature-sensitive polymer/nanoshell composites for photothermally modulated drug deliveryen_US
dc.typeUtility patenten_US
dc.type.dcmiTexten_US
dc.type.genrepatentsen_US
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