Development of a multimodal foveated endomicroscope for the detection of oral cancer

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dc.citation.firstpage1525
dc.citation.issueNumber3
dc.citation.journalTitleBiomedical Optics Express
dc.citation.lastpage1535
dc.citation.volumeNumber8
dc.contributor.authorShadfan, Adam
dc.contributor.authorDarwiche, Hawraa
dc.contributor.authorBlanco, Jesus
dc.contributor.authorGillenwater, Ann
dc.contributor.authorRichards-Kortum, Rebecca
dc.contributor.authorTkaczyk, Tomasz S.
dc.date.accessioned2017-03-07T18:24:16Z
dc.date.available2017-03-07T18:24:16Z
dc.date.issued2017
dc.description.abstractA multimodal endomicroscope was developed for cancer detection that combines hyperspectral and confocal imaging through a single foveated objective and a vibrating optical fiber bundle. Standard clinical examination has a limited ability to identify early stage oral cancer. Optical detection methods are typically restricted by either achievable resolution or a small field-of-view. By combining high resolution and widefield spectral imaging into a single probe, a device was developed that provides spectral and spatial information over a 5 mm field to locate suspicious lesions that can then be inspected in high resolution mode. The device was evaluated on ex vivo biopsies of human oral tumors.
dc.identifier.citationShadfan, Adam, Darwiche, Hawraa, Blanco, Jesus, et al.. "Development of a multimodal foveated endomicroscope for the detection of oral cancer." <i>Biomedical Optics Express,</i> 8, no. 3 (2017) The Optical Society: 1525-1535. https://doi.org/10.1364/BOE.8.001525.
dc.identifier.doihttps://doi.org/10.1364/BOE.8.001525
dc.identifier.urihttps://hdl.handle.net/1911/94025
dc.language.isoeng
dc.publisherThe Optical Society
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
dc.titleDevelopment of a multimodal foveated endomicroscope for the detection of oral cancer
dc.typeJournal article
dc.type.dcmiText
dc.type.publicationpublisher version
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