Distributed sensor and actuator networks for closed-loop bioelectronic medicine

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dc.citation.firstpage125en_US
dc.citation.journalTitleMaterials Todayen_US
dc.citation.lastpage135en_US
dc.citation.volumeNumber46en_US
dc.contributor.authorBhave, Gaurien_US
dc.contributor.authorChen, Joshua C.en_US
dc.contributor.authorSinger, Amandaen_US
dc.contributor.authorSharma, Aditien_US
dc.contributor.authorRobinson, Jacob T.en_US
dc.date.accessioned2021-06-17T19:01:20Zen_US
dc.date.available2021-06-17T19:01:20Zen_US
dc.date.issued2021en_US
dc.description.abstractDesigning implantable bioelectronic systems that continuously monitor physiological functions and simultaneously provide personalized therapeutic solutions for patients remains a persistent challenge across many applications ranging from neural systems to bioelectronic organs. Closed-loop systems typically consist of three functional blocks, namely, sensors, signal processors and actuators. An effective system, that can provide the necessary therapeutics, tailored to individual physiological factors requires a distributed network of sensors and actuators. While significant progress has been made, closed-loop systems still face many challenges before they can truly be considered as long-term solutions for many diseases. In this review, we consider three important criteria where materials play a critical role to enable implantable closed-loop systems: Specificity, Biocompatibility and Connectivity. We look at the progress made in each of these fields with respect to a specific application and outline the challenges in creating bioelectronic technologies for the future.en_US
dc.identifier.citationBhave, Gauri, Chen, Joshua C., Singer, Amanda, et al.. "Distributed sensor and actuator networks for closed-loop bioelectronic medicine." <i>Materials Today,</i> 46, (2021) Elsevier: 125-135. https://doi.org/10.1016/j.mattod.2020.12.020.en_US
dc.identifier.digital1-s2-0-S1369702120304806-mainen_US
dc.identifier.doihttps://doi.org/10.1016/j.mattod.2020.12.020en_US
dc.identifier.urihttps://hdl.handle.net/1911/110732en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.rightsThis is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/en_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/en_US
dc.titleDistributed sensor and actuator networks for closed-loop bioelectronic medicineen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpublisher versionen_US
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