Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease

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dc.citation.firstpage645en_US
dc.citation.issueNumber6en_US
dc.citation.journalTitleAlzheimer's & Dementiaen_US
dc.citation.lastpage653en_US
dc.citation.volumeNumber12en_US
dc.contributor.authorAllen, Genevera I.en_US
dc.contributor.authorAmoroso, Nicolaen_US
dc.contributor.authorAnghel, Catalinaen_US
dc.contributor.authorBalagurusamy, Venkaten_US
dc.contributor.authorBare, Christopher J.en_US
dc.contributor.authorBeaton, Dereken_US
dc.contributor.authorBellotti, Robertoen_US
dc.contributor.authorBennett, David A.en_US
dc.contributor.authorBoehme, Kevin L.en_US
dc.contributor.authorBoutros, Paul C.en_US
dc.contributor.authorCaberlotto, Lauraen_US
dc.contributor.authorCaloian, Cristianen_US
dc.contributor.authorCampbell, Fredericken_US
dc.contributor.authorNeto, Elias Chaibuben_US
dc.contributor.authorChang, Yu-Chuanen_US
dc.contributor.authorChen, Beibeien_US
dc.contributor.authorChen, Chien-Yuen_US
dc.contributor.authorChien, Ting-Yingen_US
dc.contributor.authorClark, Timen_US
dc.contributor.authorDas, Sudeshnaen_US
dc.contributor.authorDavatzikos, Christosen_US
dc.contributor.authorDeng, Jieyaoen_US
dc.contributor.authorDillenberger, Donnaen_US
dc.contributor.authorDobson, Richard J.B.en_US
dc.contributor.authorDong, Qilinen_US
dc.contributor.authorDoshi, Jimiten_US
dc.contributor.authorDuma, Deniseen_US
dc.contributor.authorErrico, Rosangelaen_US
dc.contributor.authorErus, Gurayen_US
dc.contributor.authorEverett, Evanen_US
dc.contributor.authorFardo, David W.en_US
dc.contributor.authorFriend, Stephen H.en_US
dc.contributor.authorFrӧhlich, Holgeren_US
dc.contributor.authorGan, Jessicaen_US
dc.contributor.authorSt George-Hyslop, Peteren_US
dc.contributor.authorGhosh, Satrajit S.en_US
dc.contributor.authorGlaab, Enricoen_US
dc.contributor.authorGreen, Robert C.en_US
dc.contributor.authorGuan, Yuanfangen_US
dc.contributor.authorHong, Ming-Yien_US
dc.contributor.authorHuang, Chaoen_US
dc.contributor.authorHwang, Jinseuben_US
dc.contributor.authorIbrahim, Josephen_US
dc.contributor.authorInglese, Paoloen_US
dc.contributor.authorIyappan, Anandhien_US
dc.contributor.authorJiang, Qijiaen_US
dc.contributor.authorKatsumata, Yurikoen_US
dc.contributor.authorKauwe, John S.K.en_US
dc.contributor.authorKlein, Arnoen_US
dc.contributor.authorKong, Dehanen_US
dc.contributor.authorKrause, Rolanden_US
dc.contributor.authorLalonde, Emilieen_US
dc.contributor.authorLauria, Marioen_US
dc.contributor.authorLee, Eunjeeen_US
dc.contributor.authorLin, Xihuien_US
dc.contributor.authorLiu, Zhandongen_US
dc.contributor.authorLivingstone, Julieen_US
dc.contributor.authorLogsdon, Benjamin A.en_US
dc.contributor.authorLovestone, Simonen_US
dc.contributor.authorMa, Tsung-weien_US
dc.contributor.authorMalhotra, Ashutoshen_US
dc.contributor.authorMangravite, Lara M.en_US
dc.contributor.authorMaxwell, Taylor J.en_US
dc.contributor.authorMerrill, Emilyen_US
dc.contributor.authorNagorski, Johnen_US
dc.contributor.authorNamasivayam, Aishwaryaen_US
dc.contributor.authorNarayan, Manjarien_US
dc.contributor.authorNaz, Mufassraen_US
dc.contributor.authorNewhouse, Stephen J.en_US
dc.contributor.authorNorman, Thea C.en_US
dc.contributor.authorNurtdinov, Ramil N.en_US
dc.contributor.authorOyang, Yen-Jenen_US
dc.contributor.authorPawitan, Yudien_US
dc.contributor.authorPeng, Shengwenen_US
dc.contributor.authorPeters, Mette A.en_US
dc.contributor.authorPiccolo, Stephen R.en_US
dc.contributor.authorPraveen, Paurushen_US
dc.contributor.authorPriami, Corradoen_US
dc.contributor.authorSabelnykova, Veronica Y.en_US
dc.contributor.authorSenger, Philippen_US
dc.contributor.authorShen, Xiaen_US
dc.contributor.authorSimmons, Andrewen_US
dc.contributor.authorSotiras, Aristeidisen_US
dc.contributor.authorStolovitzky, Gustavoen_US
dc.contributor.authorTangaro, Sabinaen_US
dc.contributor.authorTateo, Andreaen_US
dc.contributor.authorTung, Yi-Anen_US
dc.contributor.authorTustison, Nicholas J.en_US
dc.contributor.authorVarol, Erdemen_US
dc.contributor.authorVradenburg, Georgeen_US
dc.contributor.authorWeiner, Michael W.en_US
dc.contributor.authorXiao, Guanghuaen_US
dc.contributor.authorXie, Leien_US
dc.contributor.authorXie, Yangen_US
dc.contributor.authorXu, Jiaen_US
dc.contributor.authorYang, Hojinen_US
dc.contributor.authorZhan, Xiaoweien_US
dc.contributor.authorZhou, Yunyunen_US
dc.contributor.authorZhu, Fanen_US
dc.contributor.authorZhu, Hongtuen_US
dc.contributor.authorZhu, Shanfengen_US
dc.contributor.authorAlzheimer’s Disease Neuroimaging Initiativeen_US
dc.date.accessioned2017-05-09T20:16:06Z
dc.date.available2017-05-09T20:16:06Z
dc.date.issued2016en_US
dc.description.abstractIdentifying accurate biomarkers of cognitive decline is essential for advancing early diagnosis and prevention therapies in Alzheimer's disease. The Alzheimer's disease DREAM Challenge was designed as a computational crowdsourced project to benchmark the current state-of-the-art in predicting cognitive outcomes in Alzheimer's disease based on high dimensional, publicly available genetic and structural imaging data. This meta-analysis failed to identify a meaningful predictor developed from either data modality, suggesting that alternate approaches should be considered for prediction of cognitive performance.en_US
dc.identifier.citationAllen, Genevera I., Amoroso, Nicola, Anghel, Catalina, et al.. "Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease." <i>Alzheimer's & Dementia,</i> 12, no. 6 (2016) Elsevier: 645-653. https://doi.org/10.1016/j.jalz.2016.02.006.
dc.identifier.doihttps://doi.org/10.1016/j.jalz.2016.02.006en_US
dc.identifier.urihttps://hdl.handle.net/1911/94205
dc.language.isoengen_US
dc.publisherElsevier
dc.rightsThis is an open access article under the CC BY-NC-ND licenseen_US
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/en_US
dc.subject.keywordAzheimer’s diseaseen_US
dc.subject.keywordBiomarkersen_US
dc.subject.keywordCrowdsourceen_US
dc.subject.keywordBig dataen_US
dc.subject.keywordBioinformaticsen_US
dc.subject.keywordCognitive declineen_US
dc.subject.keywordImagingen_US
dc.subject.keywordGeneticsen_US
dc.titleCrowdsourced estimation of cognitive decline and resilience in Alzheimer's diseaseen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpublisher versionen_US
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