A total synthesis of (+,-)-quinocarcin

Simple item page
dc.contributor.advisorFukuyama, Tohru
dc.creatorNunes, Joseph John
dc.date.accessioned2009-06-04T00:37:48Z
dc.date.available2009-06-04T00:37:48Z
dc.date.issued1988
dc.description.abstractA synthetic route via the key intermediate DX-52-1 21 has resulted in the first total synthesis of the complex antitumor antibiotic quinocarcin 1. Salient features include an acyliminium ion-mediated stereoselective construction of a diazabicyclo (3.2.1) octane nucleus, a stereoselective Pictet-Spengler cyclization, and a silver assisted conversion of DX-52-1 to the title compound.(DIAGRAM, TABLE OR GRAPHIC OMITTED...PLEASE SEE DAI)
dc.format.extent172 p.en_US
dc.format.mimetypeapplication/pdf
dc.identifier.callnoThesis Chem. 1988 Nunes
dc.identifier.citationNunes, Joseph John. "A total synthesis of (+,-)-quinocarcin." (1988) Diss., Rice University. <a href="https://hdl.handle.net/1911/16174">https://hdl.handle.net/1911/16174</a>.
dc.identifier.urihttps://hdl.handle.net/1911/16174
dc.language.isoeng
dc.rightsCopyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.
dc.subjectOrganic chemistry
dc.titleA total synthesis of (+,-)-quinocarcin
dc.typeThesis
dc.type.materialText
thesis.degree.departmentChemistry
thesis.degree.disciplineNatural Sciences
thesis.degree.grantorRice University
thesis.degree.levelDoctoral
thesis.degree.nameDoctor of Philosophy
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
8900268.PDF
Size:
4.77 MB
Format:
Adobe Portable Document Format
Download
Collections
Rice University Electronic Theses and Dissertations