A total synthesis of (+,-)-quinocarcin
Date
1988
Authors
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Abstract
A synthetic route via the key intermediate DX-52-1 21 has resulted in the first total synthesis of the complex antitumor antibiotic quinocarcin 1. Salient features include an acyliminium ion-mediated stereoselective construction of a diazabicyclo (3.2.1) octane nucleus, a stereoselective Pictet-Spengler cyclization, and a silver assisted conversion of DX-52-1 to the title compound.(DIAGRAM, TABLE OR GRAPHIC OMITTED...PLEASE SEE DAI)
Description
Advisor
Degree
Doctor of Philosophy
Type
Thesis
Keywords
Organic chemistry
Citation
Nunes, Joseph John. "A total synthesis of (+,-)-quinocarcin." (1988) Diss., Rice University. https://hdl.handle.net/1911/16174.
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