Multilayered, Hyaluronic Acid-Based Hydrogel Formulations Suitable for Automated 3D High Throughput Drug Screening of Cancer-Stromal Cell Cocultures

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dc.citation.firstpage1664
dc.citation.issueNumber11
dc.citation.journalTitleAdvanced Healthcare Materials
dc.citation.lastpage1674
dc.citation.volumeNumber4
dc.contributor.authorEngel, Brian J.
dc.contributor.authorConstantinou, Pamela E.
dc.contributor.authorSablatura, Lindsey K.
dc.contributor.authorDoty, Nathaniel J.
dc.contributor.authorCarson, Daniel D.
dc.contributor.authorFarach-Carson, Mary C.
dc.contributor.authorHarrington, Daniel Anton
dc.contributor.authorZarembinski, Thomas I.
dc.date.accessioned2016-10-21T17:01:00Z
dc.date.available2016-10-21T17:01:00Z
dc.date.issued2015
dc.description.abstractValidation of a high-throughput compatible 3D hyaluronic acid hydrogel coculture of cancer cells with stromal cells. The multilayered hyaluronic acid hydrogels improve drug screening predictability as evaluated with a panel of clinically relevant chemotherapeutics in both prostate and endometrial cancer cell lines compared to 2D culture.
dc.identifier.citationEngel, Brian J., Constantinou, Pamela E., Sablatura, Lindsey K., et al.. "Multilayered, Hyaluronic Acid-Based Hydrogel Formulations Suitable for Automated 3D High Throughput Drug Screening of Cancer-Stromal Cell Cocultures." <i>Multilayered, Hyaluronic Acid-Based Hydrogel Formulations Suitable for Automated 3D High Throughput Drug Screening of Cancer-Stromal Cell Cocultures,</i> 4, no. 11 (2015) Wiley: 1664-1674. http://dx.doi.org/10.1002/adhm.201500258.
dc.identifier.doihttp://dx.doi.org/10.1002/adhm.201500258
dc.identifier.urihttps://hdl.handle.net/1911/91975
dc.language.isoeng
dc.publisherWiley
dc.rightsThis is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by Wiley.
dc.subject.keyword3D culture
dc.subject.keywordcoculture
dc.subject.keyworddrug screening
dc.subject.keywordhigh throughput
dc.subject.keywordhyaluronic acid
dc.titleMultilayered, Hyaluronic Acid-Based Hydrogel Formulations Suitable for Automated 3D High Throughput Drug Screening of Cancer-Stromal Cell Cocultures
dc.typeJournal article
dc.type.dcmiText
dc.type.publicationpost-print
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