Ultraflexible Neural Electrodes for Long-Lasting Intracortical Recording

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dc.citation.articleNumber101387
dc.citation.issueNumber8
dc.citation.journalTitleiScience
dc.citation.volumeNumber23
dc.contributor.authorHe, Fei
dc.contributor.authorLycke, Roy
dc.contributor.authorGanji, Mehran
dc.contributor.authorXie, Chong
dc.contributor.authorLuan, Lan
dc.contributor.orgNeuroEngineering Initiative
dc.date.accessioned2020-11-03T19:41:53Z
dc.date.available2020-11-03T19:41:53Z
dc.date.issued2020
dc.description.abstractImplanted electrodes provide one of the most important neurotechniques for fundamental and translational neurosciences by permitting time-resolved electrical detection of individual neurons in vivo. However, conventional rigid electrodes typically cannot provide stable, long-lasting recordings. Numerous interwoven biotic and abiotic factors at the tissue-electrode interface lead to short- and long-term instability of the recording performance. Making neural electrodes flexible provides a promising approach to mitigate these challenges on the implants and at the tissue-electrode interface. Here we review the recent progress of ultraflexible neural electrodes and discuss the engineering principles, the material properties, and the implantation strategies to achieve stable tissue-electrode interface and reliable unit recordings in living brains.
dc.identifier.citationHe, Fei, Lycke, Roy, Ganji, Mehran, et al.. "Ultraflexible Neural Electrodes for Long-Lasting Intracortical Recording." <i>iScience,</i> 23, no. 8 (2020) Cell Press: https://doi.org/10.1016/j.isci.2020.101387.
dc.identifier.doihttps://doi.org/10.1016/j.isci.2020.101387
dc.identifier.urihttps://hdl.handle.net/1911/109491
dc.language.isoeng
dc.publisherCell Press
dc.rightsThis is an open access article under the CC BY-NC-ND license
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.titleUltraflexible Neural Electrodes for Long-Lasting Intracortical Recording
dc.typeJournal article
dc.type.dcmiText
dc.type.publicationpublisher version
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