Pexophagy and peroxisomal protein turnover in plants

dc.citation.firstpage999
dc.citation.issueNumber5
dc.citation.journalTitleBiochimica et Biophysica Acta (BBA) - Molecular Cell Research
dc.citation.lastpage1005
dc.citation.volumeNumber1863
dc.contributor.authorYoung, Pierce G.
dc.contributor.authorBartel, Bonnie
dc.date.accessioned2018-07-10T18:32:40Z
dc.date.available2018-07-10T18:32:40Z
dc.date.issued2016
dc.description.abstractPeroxisomes are dynamic, vital organelles that sequester a variety of oxidative reactions and their toxic byproducts from the remainder of the cell. The oxidative nature of peroxisomal metabolism predisposes the organelle to self-inflicted damage, highlighting the need for a mechanism to dispose of damaged peroxisomes. In addition, the metabolic requirements of plant peroxisomes change during development, and obsolete peroxisomal proteins are degraded. Although pexophagy, the selective autophagy of peroxisomes, is an obvious mechanism for executing such degradation, pexophagy has only recently been described in plants. Several recent studies in the reference plant Arabidopsis thaliana implicate pexophagy in the turnover of peroxisomal proteins, both for quality control and during functional transitions of peroxisomal content. In this review, we describe our current understanding of the occurrence, roles, and mechanisms of pexophagy in plants.
dc.identifier.citationYoung, Pierce G. and Bartel, Bonnie. "Pexophagy and peroxisomal protein turnover in plants." <i>Biochimica et Biophysica Acta (BBA) - Molecular Cell Research,</i> 1863, no. 5 (2016) Elsevier: 999-1005. https://doi.org/10.1016/j.bbamcr.2015.09.005.
dc.identifier.digitalnihms721442
dc.identifier.doihttps://doi.org/10.1016/j.bbamcr.2015.09.005
dc.identifier.urihttps://hdl.handle.net/1911/102365
dc.language.isoeng
dc.publisherElsevier
dc.rightsThis is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by Elsevier.
dc.subject.keywordautophagy
dc.subject.keywordLON protease
dc.subject.keywordorganelle quality control
dc.subject.keywordperoxisome
dc.subject.keywordpexophagy
dc.subject.keywordprotein degradation
dc.titlePexophagy and peroxisomal protein turnover in plants
dc.typeJournal article
dc.type.dcmiText
dc.type.publicationpost-print
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