A statistical model for removing inter-device differences in spectroscopy

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dc.citation.firstpage7617
dc.citation.issueNumber7
dc.citation.journalTitleOptics Express
dc.citation.lastpage7624
dc.citation.volumeNumber22
dc.contributor.authorWang, Lu
dc.contributor.authorLee, Jong Soo
dc.contributor.authorLane, Pierre
dc.contributor.authorAtkinson, E. Neely
dc.contributor.authorZuluaga, Andres
dc.contributor.authorFollen, Michele
dc.contributor.authorMacAulay, Calum
dc.contributor.authorCox, Dennis D.
dc.date.accessioned2014-04-14T20:56:34Z
dc.date.available2014-04-14T20:56:34Z
dc.date.issued2014
dc.description.abstractWe are investigating spectroscopic devices designed to make in vivo cervical tissue measurements to detect pre-cancerous and cancerous lesions. All devices have the same design and ideally should record identical measurements. However, we observed consistent differences among them. An experiment was designed to study the sources of variation in the measurements recorded. Here we present a log additive statistical model that incorporates the sources of variability we identified. Based on this model, we estimated correction factors from the experimental data needed to eliminate the inter-device variability and other sources of variation. These correction factors are intended to improve the accuracy and repeatability of such devices when making future measurements on patient tissue.
dc.identifier.citationWang, Lu, Lee, Jong Soo, Lane, Pierre, et al.. "A statistical model for removing inter-device differences in spectroscopy." <i>Optics Express,</i> 22, no. 7 (2014) Optical Society of America: 7617-7624. http://dx.doi.org/10.1364/OE.22.007617.
dc.identifier.doihttp://dx.doi.org/10.1364/OE.22.007617
dc.identifier.urihttps://hdl.handle.net/1911/75891
dc.language.isoeng
dc.publisherOptical Society of America
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
dc.titleA statistical model for removing inter-device differences in spectroscopy
dc.typeJournal article
dc.type.dcmiText
dc.type.publicationpublisher version
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