Anthropogenic Carbon Nanotubes Found in the Airways of Parisian Children

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dc.citation.firstpage1697
dc.citation.issueNumber11
dc.citation.journalTitleEBioMedicine
dc.citation.lastpage1704
dc.citation.volumeNumber2
dc.contributor.authorKolosnjaj-Tabi, Jelena
dc.contributor.authorJust, Jocelyne
dc.contributor.authorHartman, Keith B.
dc.contributor.authorLaoudi, Yacine
dc.contributor.authorBoudjemaa, Sabah
dc.contributor.authorAlloyeau, Damien
dc.contributor.authorSzwarc, Henri
dc.contributor.authorWilson, Lon J.
dc.contributor.authorMoussa, Fathi
dc.contributor.orgRichard E. Smalley Institute for Nanoscale Science and Technology
dc.date.accessioned2016-01-15T19:47:52Z
dc.date.available2016-01-15T19:47:52Z
dc.date.issued2015
dc.description.abstractCompelling evidence shows that fine particulate matters (PMs) from air pollution penetrate lower airways and are associated with adverse health effects even within concentrations below those recommended by the WHO. A paper reported a dose-dependent link between carbon content in alveolar macrophages (assessed only by optical microscopy) and the decline in lung function. However, to the best of our knowledge, PM had never been accurately characterized inside human lung cells and the most responsible components of the particulate mix are still unknown. On another hand carbon nanotubes (CNTs) from natural and anthropogenic sources might be an important component of PM in both indoor and outdoor air. We used high-resolution transmission electron microscopy and energy dispersive X-ray spectroscopy to characterize PM present in broncho-alveolar lavage-fluids (n = 64) and inside lung cells (n = 5 patients) of asthmatic children. We show that inhaled PM mostly consist of CNTs. These CNTs are present in all examined samples and they are similar to those we found in dusts and vehicle exhausts collected in Paris, as well as to those previously characterized in ambient air in the USA, in spider webs in India, and in ice core. These results strongly suggest that humans are routinely exposed to CNTs.
dc.identifier.citationKolosnjaj-Tabi, Jelena, Just, Jocelyne, Hartman, Keith B., et al.. "Anthropogenic Carbon Nanotubes Found in the Airways of Parisian Children." <i>EBioMedicine,</i> 2, no. 11 (2015) Elsevier: 1697-1704. http://dx.doi.org/10.1016/j.ebiom.2015.10.012.
dc.identifier.doihttp://dx.doi.org/10.1016/j.ebiom.2015.10.012
dc.identifier.urihttps://hdl.handle.net/1911/87858
dc.language.isoeng
dc.publisherElsevier
dc.rightsThis is an open access article under the CC BY-NC-ND license.
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.keywordair pollution
dc.subject.keywordasthma
dc.subject.keywordcarbon
dc.subject.keywordnanotubes
dc.subject.keywordLamellar bodies
dc.titleAnthropogenic Carbon Nanotubes Found in the Airways of Parisian Children
dc.typeJournal article
dc.type.dcmiText
dc.type.publicationpublisher version
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