Confluent and nonconfluent phases in a model of cell tissue

dc.citation.articleNumber042418
dc.citation.issueNumber4
dc.citation.journalTitlePhysical Review E
dc.citation.volumeNumber98
dc.contributor.authorTeomy, Eial
dc.contributor.authorKessler, David A.
dc.contributor.authorLevine, Herbert
dc.date.accessioned2019-01-09T17:21:09Z
dc.date.available2019-01-09T17:21:09Z
dc.date.issued2018
dc.description.abstractThe Voronoi-based cellular model is highly successful in describing the motion of two-dimensional confluent cell tissues. In the homogeneous version of this model, the energy of each cell is determined solely by its geometric shape and size, and the interaction between adjacent cells is a by-product of this additive energy. We generalize this model so as to allow zero or partial contact between cells. We identify several phases, two of which (solid confluent and liquid confluent) were found in previous studies that imposed confluency as well as others that were not. Transitions in this model may be relevant for understanding both normal development as well as cancer metastasis.
dc.identifier.citationTeomy, Eial, Kessler, David A. and Levine, Herbert. "Confluent and nonconfluent phases in a model of cell tissue." <i>Physical Review E,</i> 98, no. 4 (2018) American Physical Society: https://doi.org/10.1103/PhysRevE.98.042418.
dc.identifier.digitalPhysRevE.98.042418
dc.identifier.doihttps://doi.org/10.1103/PhysRevE.98.042418
dc.identifier.urihttps://hdl.handle.net/1911/105022
dc.language.isoeng
dc.publisherAmerican Physical Society
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
dc.titleConfluent and nonconfluent phases in a model of cell tissue
dc.typeJournal article
dc.type.dcmiText
dc.type.publicationpublisher version
Files
Original bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
PhysRevE.98.042418.pdf
Size:
1.34 MB
Format:
Adobe Portable Document Format