A High-Value, Low-Cost Bubble Continuous Positive Airway Pressure System for Low-Resource Settings: Technical Assessment and Initial Case Reports

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dc.citation.firstpagee53622
dc.citation.issueNumber1
dc.citation.journalTitlePLoS One
dc.citation.volumeNumber8
dc.contributor.authorBrown, Jocelyn
dc.contributor.authorMachen, Heather
dc.contributor.authorKawaza, Kondwani
dc.contributor.authorMwanza, Zondiwe
dc.contributor.authorIniguez, Suzanne
dc.contributor.authorLang, Hans
dc.contributor.authorGest, Alfred
dc.contributor.authorKennedy, Neil
dc.contributor.authorMiros, Robert
dc.contributor.authorRichards-Kortum, Rebecca
dc.contributor.authorMolyneux, Elizabeth
dc.contributor.authorOden, Maria
dc.date.accessioned2013-03-18T20:36:42Z
dc.date.available2013-03-18T20:36:42Z
dc.date.issued2013
dc.description.abstractAcute respiratory infections are the leading cause of global child mortality. In the developing world, nasal oxygen therapy is often the only treatment option for babies who are suffering from respiratory distress. Without the added pressure of bubble Continuous Positive Airway Pressure (bCPAP) which helps maintain alveoli open, babies struggle to breathe and can suffer serious complications, and frequently death. A stand-alone bCPAP device can cost $6,000, too expensive for most developing world hospitals. Here, we describe the design and technical evaluation of a new, rugged bCPAP system that can be made in small volume for a cost-of-goods of approximately $350. Moreover, because of its simple designﾗconsumergrade pumps, medical tubing, and regulators—it requires only the simple replacement of a ,$1 diaphragm approximately every 2 years for maintenance. The low-cost bCPAP device delivers pressure and flow equivalent to those of a reference bCPAP system used in the developed world. We describe the initial clinical cases of a child with bronchiolitis and a neonate with respiratory distress who were treated successfully with the new bCPAP device.
dc.embargo.termsnone
dc.identifier.citationBrown, Jocelyn, Machen, Heather, Kawaza, Kondwani, et al.. "A High-Value, Low-Cost Bubble Continuous Positive Airway Pressure System for Low-Resource Settings: Technical Assessment and Initial Case Reports." <i>PLoS One,</i> 8, no. 1 (2013) Public Library of Science: e53622. http://dx.doi.org/10.1371/journal.pone.0053622.
dc.identifier.doihttp://dx.doi.org/10.1371/journal.pone.0053622
dc.identifier.urihttps://hdl.handle.net/1911/70700
dc.language.isoeng
dc.publisherPublic Library of Science
dc.rightsThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleA High-Value, Low-Cost Bubble Continuous Positive Airway Pressure System for Low-Resource Settings: Technical Assessment and Initial Case Reports
dc.typeJournal article
dc.type.dcmiText
dc.type.publicationpublisher version
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