A High-Value, Low-Cost Bubble Continuous Positive Airway Pressure System for Low-Resource Settings: Technical Assessment and Initial Case Reports

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dc.citation.firstpagee53622en_US
dc.citation.issueNumber1en_US
dc.citation.journalTitlePLoS Oneen_US
dc.citation.volumeNumber8en_US
dc.contributor.authorBrown, Jocelynen_US
dc.contributor.authorMachen, Heatheren_US
dc.contributor.authorKawaza, Kondwanien_US
dc.contributor.authorMwanza, Zondiween_US
dc.contributor.authorIniguez, Suzanneen_US
dc.contributor.authorLang, Hansen_US
dc.contributor.authorGest, Alfreden_US
dc.contributor.authorKennedy, Neilen_US
dc.contributor.authorMiros, Roberten_US
dc.contributor.authorRichards-Kortum, Rebeccaen_US
dc.contributor.authorMolyneux, Elizabethen_US
dc.contributor.authorOden, Mariaen_US
dc.date.accessioned2013-03-18T20:36:42Zen_US
dc.date.available2013-03-18T20:36:42Zen_US
dc.date.issued2013en_US
dc.description.abstractAcute respiratory infections are the leading cause of global child mortality. In the developing world, nasal oxygen therapy is often the only treatment option for babies who are suffering from respiratory distress. Without the added pressure of bubble Continuous Positive Airway Pressure (bCPAP) which helps maintain alveoli open, babies struggle to breathe and can suffer serious complications, and frequently death. A stand-alone bCPAP device can cost $6,000, too expensive for most developing world hospitals. Here, we describe the design and technical evaluation of a new, rugged bCPAP system that can be made in small volume for a cost-of-goods of approximately $350. Moreover, because of its simple designﾗconsumergrade pumps, medical tubing, and regulators—it requires only the simple replacement of a ,$1 diaphragm approximately every 2 years for maintenance. The low-cost bCPAP device delivers pressure and flow equivalent to those of a reference bCPAP system used in the developed world. We describe the initial clinical cases of a child with bronchiolitis and a neonate with respiratory distress who were treated successfully with the new bCPAP device.en_US
dc.embargo.termsnoneen_US
dc.identifier.citationBrown, Jocelyn, Machen, Heather, Kawaza, Kondwani, et al.. "A High-Value, Low-Cost Bubble Continuous Positive Airway Pressure System for Low-Resource Settings: Technical Assessment and Initial Case Reports." <i>PLoS One,</i> 8, no. 1 (2013) Public Library of Science: e53622. http://dx.doi.org/10.1371/journal.pone.0053622.en_US
dc.identifier.doihttp://dx.doi.org/10.1371/journal.pone.0053622en_US
dc.identifier.urihttps://hdl.handle.net/1911/70700en_US
dc.language.isoengen_US
dc.publisherPublic Library of Scienceen_US
dc.rightsThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en_US
dc.titleA High-Value, Low-Cost Bubble Continuous Positive Airway Pressure System for Low-Resource Settings: Technical Assessment and Initial Case Reportsen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpublisher versionen_US
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