Epothilone analogs, methods of synthesis, methods of treatment, and drug conjugates thereof

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dc.contributor.assigneeRice University
dc.contributor.publisherUnited States Patent and Trademark Office
dc.creatorNicolaou, Kyriacos C.
dc.creatorRhoades, Derek
dc.creatorWang, Yanping
dc.creatorTotokotsopoulos, Sotirios
dc.date.accessioned2021-03-02T23:41:41Z
dc.date.available2021-03-02T23:41:41Z
dc.date.filed2016-10-14
dc.date.issued2020-12-29
dc.description.abstract"In one aspect, the present disclosure provides epothilone analogs of the formula (I) wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. Additionally, drug conjugates with cell targeting moieties of the compounds are also provided. "
dc.digitization.specificationsThis patent information was downloaded from the US Patent and Trademark website (http://www.uspto.gov/) as image-PDFs. The PDFs were OCRed for access purposes
dc.format.extent118
dc.identifier.citationNicolaou, Kyriacos C., Rhoades, Derek, Wang, Yanping and Totokotsopoulos, Sotirios, "Epothilone analogs, methods of synthesis, methods of treatment, and drug conjugates thereof." Patent US10874646B2. issued 2020-12-29. Retrieved from <a href="https://hdl.handle.net/1911/110126">https://hdl.handle.net/1911/110126</a>.
dc.identifier.patentIDUS10874646B2
dc.identifier.urihttps://hdl.handle.net/1911/110126
dc.language.isoeng
dc.titleEpothilone analogs, methods of synthesis, methods of treatment, and drug conjugates thereof
dc.typeUtility patent
dc.type.dcmiText
dc.type.genrepatents
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