Epothilone analogs, methods of synthesis, methods of treatment, and drug conjugates thereof

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dc.contributor.assigneeRice Universityen_US
dc.contributor.publisherUnited States Patent and Trademark Officeen_US
dc.creatorNicolaou, Kyriacos C.en_US
dc.creatorRhoades, Dereken_US
dc.creatorWang, Yanpingen_US
dc.creatorTotokotsopoulos, Sotiriosen_US
dc.date.accessioned2021-03-02T23:41:41Zen_US
dc.date.available2021-03-02T23:41:41Zen_US
dc.date.filed2016-10-14en_US
dc.date.issued2020-12-29en_US
dc.description.abstract"In one aspect, the present disclosure provides epothilone analogs of the formula (I) wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. Additionally, drug conjugates with cell targeting moieties of the compounds are also provided. "en_US
dc.digitization.specificationsThis patent information was downloaded from the US Patent and Trademark website (http://www.uspto.gov/) as image-PDFs. The PDFs were OCRed for access purposesen_US
dc.format.extent118en_US
dc.identifier.citationNicolaou, Kyriacos C., Rhoades, Derek, Wang, Yanping and Totokotsopoulos, Sotirios, "Epothilone analogs, methods of synthesis, methods of treatment, and drug conjugates thereof." Patent US10874646B2. issued 2020-12-29. Retrieved from <a href="https://hdl.handle.net/1911/110126">https://hdl.handle.net/1911/110126</a>.en_US
dc.identifier.patentIDUS10874646B2en_US
dc.identifier.urihttps://hdl.handle.net/1911/110126en_US
dc.language.isoengen_US
dc.titleEpothilone analogs, methods of synthesis, methods of treatment, and drug conjugates thereofen_US
dc.typeUtility patenten_US
dc.type.dcmiTexten_US
dc.type.genrepatentsen_US
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