Confocal foveated endomicroscope for the detection of esophageal carcinoma
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By mimicking the variable resolution of the human eye, a newly designed foveated endomicroscopic objective shows the potential to improve current endoscopic based techniques of identifying abnormal tissue in the esophagus and colon. The prototype miniature foveated objective is imaged with a confocal microscope to provide large field of view images combined with a high resolution central region to rapidly observe morphological structures associated with cancer development in a mouse model.
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Shadfan, Adam, Hellebust, Anne, Richards-Kortum, Rebecca, et al.. "Confocal foveated endomicroscope for the detection of esophageal carcinoma." ᅠBiomedical Optics Express, 6, no. 7 (2015) The Optical Society: 2311-2324. http://dx.doi.org/10.1364/BOE.6.002311.