Size-dependent impacts of silver nanoparticles on the lifespan, fertility, growth, and locomotion of Caenorhabditis elegans

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dc.citation.firstpage2716en_US
dc.citation.issueNumber12en_US
dc.citation.journalTitleEnvironmental Toxicology and Chemistryen_US
dc.citation.lastpage2723en_US
dc.citation.volumeNumber33en_US
dc.contributor.authorContreras, Elizabeth Q.en_US
dc.contributor.authorPuppala, Hema L.en_US
dc.contributor.authorEscalera, Gabrielaen_US
dc.contributor.authorZhong, Weiweien_US
dc.contributor.authorColvin, Vicki L.en_US
dc.date.accessioned2016-01-19T19:19:42Zen_US
dc.date.available2016-01-19T19:19:42Zen_US
dc.date.issued2014en_US
dc.description.abstractThe increased bioavailability of nanoparticles engineered for good dispersion in water may have biological and environmental impacts. To examine this issue, the authors assessed the biological effects in nematodes as they relate to exposure to silver nanoparticles (AgNPs) of different sizes at low (1 mg/L Ag), medium (10 mg/L Ag), and high concentrations (100 mg/L Ag). Over multiple generations, the authors found that the smallest particle, at 2 nm, had a notable impact on nematode fertility. In contrast, the largest particle, at 10 nm, significantly reduced the lifespan of parent nematodes (P0) by 28.8% and over the span of 3 generations (F1–F3). In addition, a computer vision system automatically measured the adverse effects in body length and motility, which were not size-dependent.en_US
dc.identifier.citationContreras, Elizabeth Q., Puppala, Hema L., Escalera, Gabriela, et al.. "Size-dependent impacts of silver nanoparticles on the lifespan, fertility, growth, and locomotion of Caenorhabditis elegans." <i>Environmental Toxicology and Chemistry,</i> 33, no. 12 (2014) Wiley: 2716-2723. http://dx.doi.org/10.1002/etc.2705.en_US
dc.identifier.doihttp://dx.doi.org/10.1002/etc.2705en_US
dc.identifier.urihttps://hdl.handle.net/1911/87883en_US
dc.language.isoengen_US
dc.publisherWileyen_US
dc.rightsThis is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by Wiley.en_US
dc.subject.keywordCaenorhabditis elegansen_US
dc.subject.keywordsilver nanoparticleen_US
dc.subject.keywordmultigenerationalen_US
dc.subject.keywordtoxicityen_US
dc.subject.keywordEscherichia colien_US
dc.titleSize-dependent impacts of silver nanoparticles on the lifespan, fertility, growth, and locomotion of Caenorhabditis elegansen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpost-printen_US
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