Finite element analysis of screw fixation durability under multiple boundary and loading conditions for a custom pelvic implant

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dc.citation.articleNumber103930en_US
dc.citation.journalTitleMedical Engineering & Physicsen_US
dc.citation.volumeNumber111en_US
dc.contributor.authorZhu, Yuhuien_US
dc.contributor.authorBabazadeh-Naseri, Ataen_US
dc.contributor.authorDunbar, Nicholas J.en_US
dc.contributor.authorBrake, Matthew R.W.en_US
dc.contributor.authorZandiyeh, Payamen_US
dc.contributor.authorLi, Gengen_US
dc.contributor.authorLeardini, Albertoen_US
dc.contributor.authorSpazzoli, Benedettaen_US
dc.contributor.authorFregly, Benjamin J.en_US
dc.date.accessioned2023-01-27T14:47:04Zen_US
dc.date.available2023-01-27T14:47:04Zen_US
dc.date.issued2023en_US
dc.description.abstractDespite showing promising functional outcomes for pelvic reconstruction after sarcoma resection, custom-made pelvic implants continue to exhibit high complication rates due to fixation failures. Patient-specific finite element models have been utilized by researchers to evaluate implant durability. However, the effect of assumed boundary and loading conditions on failure analysis results of fixation screws remains unknown. In this study, the postoperative stress distributions in the fixation screws of a state-of-the-art custom-made pelvic implant were simulated, and the risk of failure was estimated under various combinations of two bone-implant interaction models (tied vs. frictional contact) and four load cases from level-ground walking and stair activities. The study found that the average weighted peak von Mises stress could increase by 22-fold when the bone-implant interactions were modeled with a frictional contact model instead of a tied model, and the likelihood of fatigue and pullout failure for each screw could change dramatically when different combinations of boundary and loading conditions were used. The inclusion of additional boundary and loading conditions led to a more reliable analysis of fixation durability. These findings demonstrated the importance of simulating multiple boundary conditions and load cases for comprehensive implant design evaluation using finite element analysis.en_US
dc.identifier.citationZhu, Yuhui, Babazadeh-Naseri, Ata, Dunbar, Nicholas J., et al.. "Finite element analysis of screw fixation durability under multiple boundary and loading conditions for a custom pelvic implant." <i>Medical Engineering & Physics,</i> 111, (2023) Elsevier: https://doi.org/10.1016/j.medengphy.2022.103930.en_US
dc.identifier.digital1-s2-0-S1350453322001783-mainen_US
dc.identifier.doihttps://doi.org/10.1016/j.medengphy.2022.103930en_US
dc.identifier.urihttps://hdl.handle.net/1911/114242en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.rightsThis is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).en_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/).en_US
dc.titleFinite element analysis of screw fixation durability under multiple boundary and loading conditions for a custom pelvic implanten_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpublisher versionen_US
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