High processivity polymerases

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dc.contributor.assigneeRice Universityen_US
dc.contributor.publisherUnited States Patent and Trademark Officeen_US
dc.creatorShamoo, Yousif A.en_US
dc.creatorSun, Siyangen_US
dc.date.accessioned2015-05-04T19:06:07Zen_US
dc.date.available2015-05-04T19:06:07Zen_US
dc.date.filed2007-11-27en_US
dc.date.issued2014-06-10en_US
dc.description.abstractChimeric proteins comprising a sequence nonspecific single-stranded nucleic-acid-binding domain joined to a catalytic nucleic-acid-modifying domain are provided. Methods comprising contacting a nucleic acid molecule with a chimeric protein, as well as systems comprising a nucleic acid molecule, a chimeric protein, and an aqueous solution are also provided. The joining of sequence nonspecific single-stranded nucleic-acid-binding domain and a catalytic nucleic-acid-modifying domain in chimeric proteins, among other things, may prevent the separation of the two domains due to their weak association and thereby enhances processivity while maintaining fidelity.en_US
dc.digitization.specificationsThis patent information was downloaded from the US Patent and Trademark website (http://www.uspto.gov/) as image-PDFs. The PDFs were OCRed for access purposes.en_US
dc.format.extent18 ppen_US
dc.identifier.citationShamoo, Yousif A. and Sun, Siyang, "High processivity polymerases." Patent US8748147B2. issued 2014-06-10. Retrieved from https://hdl.handle.net/1911/80159.en_US
dc.identifier.patentIDUS8748147B2en_US
dc.identifier.urihttps://hdl.handle.net/1911/80159en_US
dc.language.isoengen_US
dc.titleHigh processivity polymerasesen_US
dc.typeUtility patenten_US
dc.type.dcmiTexten_US
dc.type.genrepatentsen_US
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