High processivity polymerases
| dc.contributor.assignee | Rice University | en_US |
| dc.contributor.publisher | United States Patent and Trademark Office | en_US |
| dc.creator | Shamoo, Yousif A. | en_US |
| dc.creator | Sun, Siyang | en_US |
| dc.date.accessioned | 2015-05-04T19:06:07Z | |
| dc.date.available | 2015-05-04T19:06:07Z | |
| dc.date.filed | 2007-11-27 | en_US |
| dc.date.issued | 2014-06-10 | en_US |
| dc.description.abstract | Chimeric proteins comprising a sequence nonspecific single-stranded nucleic-acid-binding domain joined to a catalytic nucleic-acid-modifying domain are provided. Methods comprising contacting a nucleic acid molecule with a chimeric protein, as well as systems comprising a nucleic acid molecule, a chimeric protein, and an aqueous solution are also provided. The joining of sequence nonspecific single-stranded nucleic-acid-binding domain and a catalytic nucleic-acid-modifying domain in chimeric proteins, among other things, may prevent the separation of the two domains due to their weak association and thereby enhances processivity while maintaining fidelity. | en_US |
| dc.digitization.specifications | This patent information was downloaded from the US Patent and Trademark website (http://www.uspto.gov/) as image-PDFs. The PDFs were OCRed for access purposes. | en_US |
| dc.format.extent | 18 pp | en_US |
| dc.identifier.citation | Shamoo, Yousif A. and Sun, Siyang, "High processivity polymerases." Patent US8748147B2. issued 2014-06-10. Retrieved from https://hdl.handle.net/1911/80159. | |
| dc.identifier.patentID | US8748147B2 | en_US |
| dc.identifier.uri | https://hdl.handle.net/1911/80159 | |
| dc.language.iso | eng | en_US |
| dc.title | High processivity polymerases | en_US |
| dc.type | Utility patent | en_US |
| dc.type.dcmi | Text | en_US |
| dc.type.genre | patents | en_US |
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