Design of a parallel-group balanced controlled trial to test the effects of assist-as-needed robotic therapy

Simple item page
dc.citation.firstpage840en_US
dc.citation.journalTitle2015 IEEE International Conference on Rehabilitation Robotics (ICORR)en_US
dc.citation.lastpage845en_US
dc.contributor.authorSergi, Fabrizioen_US
dc.contributor.authorPehlivan, Ali Utkuen_US
dc.contributor.authorFitle, Kyleen_US
dc.contributor.authorNedley, Kathrynen_US
dc.contributor.authorYozbatiran, Nurayen_US
dc.contributor.authorFrancisco, Gerard E.en_US
dc.contributor.authorO’Malley, Marcia K.en_US
dc.contributor.orgMechatronics and Haptic Interfaces Laboratoryen_US
dc.date.accessioned2016-01-20T19:40:21Zen_US
dc.date.available2016-01-20T19:40:21Zen_US
dc.date.issued2015en_US
dc.description.abstractIn this methods paper, we report on the design of a clinical study testing the efficacy of a newly developed control scheme for robot-aided rehabilitation. To measure the value added by a new control scheme, we pursued a parallel-group controlled clinical study design. This approach enables comparing the effects of the novel scheme, based on the Assist-As-Needed (AAN) paradigm, with those of a less sophisticated, fixed gain, Subject-Triggered (ST) controller. We describe the steps followed in the design of this clinical study, including details on the implementation of the two control modes, and a power analysis to determine the required number of subjects to test a clinically significant difference hypothesis. Finally, we present a method for sequential group assignment with co-variates minimization, capable of guaranteeing a desired level of balance of prognostic factors in the two study groups, a crucial requisite for small-scale clinical studies in rehabilitation. To the best of our knowledge, the study presented is the first one testing, in a controlled fashion, the differential effects of a specific control mode in upper extremity rehabilitation after incomplete spinal cord injury.en_US
dc.identifier.citationSergi, Fabrizio, Pehlivan, Ali Utku, Fitle, Kyle, et al.. "Design of a parallel-group balanced controlled trial to test the effects of assist-as-needed robotic therapy." <i>2015 IEEE International Conference on Rehabilitation Robotics (ICORR),</i> (2015) IEEE: 840-845. http://dx.doi.org/10.1109/ICORR.2015.7281307.en_US
dc.identifier.doihttp://dx.doi.org/10.1109/ICORR.2015.7281307en_US
dc.identifier.urihttps://hdl.handle.net/1911/87886en_US
dc.language.isoengen_US
dc.publisherIEEEen_US
dc.rightsThis is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by IEEE.en_US
dc.titleDesign of a parallel-group balanced controlled trial to test the effects of assist-as-needed robotic therapyen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpost-printen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
RNDM_vs_MNM_3.pdf
Size:
1.5 MB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Faculty Publications
Mechanical Engineering Publications