A Microfluidic Device for Sorting Cells According to Suspended Nanoelectrode Electrophysiology

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dc.contributor.advisorRobinson, Jacob T
dc.creatorBell, Andrew
dc.date.accessioned2019-05-16T19:54:10Z
dc.date.available2019-05-16T19:54:10Z
dc.date.created2017-12
dc.date.issued2017-08-14
dc.date.submittedDecember 2017
dc.date.updated2019-05-16T19:54:10Z
dc.description.abstractElectrically active tissues and cells are found in all kingdoms of life and allow us to perceive, process, and impact our environment. Despite the ubiquity and importance of electrical activity in biology, the genes and proteins controlling many electrically dependent abilities remain incompletely characterized. Electrically excitable cells are highly specialized, frequently resulting in a high degree of heterogeneity, and when analyzing at a population level, the proteins or genes responsible for the behavior of a few cells are quickly drowned out. To facilitate separation of subpopulations of electrically active cells, we have designed, fabricated, and tested a device incorporating nanoelectrodes into a micro uidic chip for sorting cells based on their electrophysiology.
dc.format.mimetypeapplication/pdf
dc.identifier.citationBell, Andrew. "A Microfluidic Device for Sorting Cells According to Suspended Nanoelectrode Electrophysiology." (2017) Master’s Thesis, Rice University. <a href="https://hdl.handle.net/1911/105449">https://hdl.handle.net/1911/105449</a>.
dc.identifier.urihttps://hdl.handle.net/1911/105449
dc.language.isoeng
dc.rightsCopyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.
dc.subjectmicrofluidic
dc.subjectelectrophyisiology
dc.subjectnanowire
dc.subjectnanoelectrode
dc.subjectsuspended nanoelectrode
dc.titleA Microfluidic Device for Sorting Cells According to Suspended Nanoelectrode Electrophysiology
dc.typeThesis
dc.type.dcmiImage
dc.type.materialText
thesis.degree.departmentApplied Physics
thesis.degree.disciplineNatural Sciences
thesis.degree.grantorRice University
thesis.degree.levelMasters
thesis.degree.majorApplied Physics/Electrical Eng
thesis.degree.nameMaster of Science
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