Improved Analysis for Determining Diffusion Coefficients from Short, Single-Molecule Trajectories with Photoblinking

Simple item page
dc.citation.firstpage228en_US
dc.citation.issueNumber1en_US
dc.citation.journalTitleLangmuiren_US
dc.citation.lastpage234en_US
dc.citation.volumeNumber29en_US
dc.contributor.authorShuang, Boen_US
dc.contributor.authorByers, Chad P.en_US
dc.contributor.authorKisley, Lydiaen_US
dc.contributor.authorWang, Lin-Yungen_US
dc.contributor.authorZhao, Juliaen_US
dc.contributor.authorMorimura, Hiroyukien_US
dc.contributor.authorLink, Stephanen_US
dc.contributor.authorLandes, Christy F.en_US
dc.contributor.orgRice Quantum Instituteen_US
dc.date.accessioned2014-12-15T20:35:10Zen_US
dc.date.available2014-12-15T20:35:10Zen_US
dc.date.issued2013en_US
dc.description.abstractTwo Maximum Likelihood Estimation (MLE) methods were developed for optimizing the analysis of single-molecule trajectories that include phenomena such as experimental noise, photoblinking, photobleaching, and translation or rotation out of the collection plane. In particular,short, single-molecule trajectories with photoblinking were studied, and our method was compared with existing analytical techniques applied to simulated data. The optimal method for various experimental cases was established, and the optimized MLE method was applied to a real experimental system: single-molecule diffusion of fluorescent molecular machines known as nanocars.en_US
dc.identifier.citationShuang, Bo, Byers, Chad P., Kisley, Lydia, et al.. "Improved Analysis for Determining Diffusion Coefficients from Short, Single-Molecule Trajectories with Photoblinking." <i>Langmuir,</i> 29, no. 1 (2013) American Chemical Society: 228-234. http://dx.doi.org/10.1021/la304063j.en_US
dc.identifier.doihttp://dx.doi.org/10.1021/la304063jen_US
dc.identifier.urihttps://hdl.handle.net/1911/78758en_US
dc.language.isoengen_US
dc.publisherAmerican Chemical Societyen_US
dc.rightsThis is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by the American Chemical Society.en_US
dc.titleImproved Analysis for Determining Diffusion Coefficients from Short, Single-Molecule Trajectories with Photoblinkingen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpost-printen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
nihms-430731.pdf
Size:
1.4 MB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Faculty Publications
Chemistry Publications
ECE Publications