Graphene–protein field effect biosensors: glucose sensing

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dc.citation.firstpage513en_US
dc.citation.issueNumber9en_US
dc.citation.journalTitleMaterials Todayen_US
dc.citation.lastpage522en_US
dc.citation.volumeNumber18en_US
dc.contributor.authorViswanathan, Sowmyaen_US
dc.contributor.authorNarayanan, Tharangattu N.en_US
dc.contributor.authorAran, Kianaen_US
dc.contributor.authorFink, Kathryn D.en_US
dc.contributor.authorParedes, Jacoboen_US
dc.contributor.authorAjayan, Pulickel M.en_US
dc.contributor.authorFilipek, Slawomiren_US
dc.contributor.authorMiszta, Przemyslawen_US
dc.contributor.authorTekin, H. Cumhuren_US
dc.contributor.authorInci, Fatihen_US
dc.contributor.authorDemirci, Utkanen_US
dc.contributor.authorLi, Pingzuoen_US
dc.contributor.authorBolotin, Kirill I.en_US
dc.contributor.authorLiepmann, Dorianen_US
dc.contributor.authorRenugopalakrishanan, V.en_US
dc.date.accessioned2015-10-27T18:12:09Zen_US
dc.date.available2015-10-27T18:12:09Zen_US
dc.date.issued2015en_US
dc.description.abstractChronic diseases are becoming more prevalent, and the complexities of managing patients continue to escalate, since their care must be balanced between the home and clinical settings. Diabetes is the most advanced example, where self-monitoring has been shown to be necessary. Glucometers are point-of-care (POC) devices that have become standard platforms at home and clinical settings. Similarly, many other POC biosensors have also been developed. Enzymes are often used in these sensors because of their specificity and the reaction products can be electrochemically transduced for the measurement. When enzymes are immobilized to an electronically active substrate, enzymatic reactions can be transduced by direct electron transport. This paper describes an approach for the development of graphene-based POC devices. This includes modifying enzymes for improved performance, developing methods to bind them to the graphene surface, incorporation of the functionalized graphene on a field-effect transistor (FET), and integration into a microfluidic device suitable for home use. This paper describes an approach for the development of a graphene-based POC biosensor platform using glucose as an example of target molecule.en_US
dc.identifier.citationViswanathan, Sowmya, Narayanan, Tharangattu N., Aran, Kiana, et al.. "Graphene–protein field effect biosensors: glucose sensing." <i>Materials Today,</i> 18, no. 9 (2015) Elsevier: 513-522. http://dx.doi.org/10.1016/j.mattod.2015.04.003.en_US
dc.identifier.doihttp://dx.doi.org/10.1016/j.mattod.2015.04.003en_US
dc.identifier.urihttps://hdl.handle.net/1911/81932en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.rightsThis is an open access article under the CC BY-NC-ND license.en_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en_US
dc.titleGraphene–protein field effect biosensors: glucose sensingen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpublisher versionen_US
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