High-resolution microendoscopy in differentiating neoplastic from non-neoplastic colorectal polyps

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dc.citation.firstpage663en_US
dc.citation.issueNumber4en_US
dc.citation.journalTitleBest Practice & Research Clinical Gastroenterologyen_US
dc.citation.lastpage673en_US
dc.citation.volumeNumber29en_US
dc.contributor.authorLouie, Justin S.en_US
dc.contributor.authorShukla, Richaen_US
dc.contributor.authorRichards-Kortum, Rebeccaen_US
dc.contributor.authorAnandasabapathy, Sharmilaen_US
dc.contributor.orgBioengineeringen_US
dc.date.accessioned2016-10-21T17:01:00Zen_US
dc.date.available2016-10-21T17:01:00Zen_US
dc.date.issued2015en_US
dc.description.abstractColorectal cancer is one of the leading causes of death worldwide. The progression from adenoma to cancer is a well known phenomenon. Current clinical practice favors colonoscopy as the preferred modality for colorectal cancer screening. Many novel endoscopic technologies are emerging for the purposes of performing "optical biopsy" to allow real-time histologic diagnosis of polyps. High resolution microendoscopy is a low-cost endoscopic technology that has demonstrated high sensitivity and specificity in differentiating neoplastic and non-neoplastic polyps. With the ability to make real-time conclusions based on the endoscopic appearance of polyps, it is becoming increasingly possible to decrease the rate of unnecessary polypectomies and utilize a "resect and discard" strategy to decrease costs of pathology evaluation. Future directions for this technology include surveillance of premalignant conditions such as inflammatory bowel disease. Moreover, the low cost and relative ease of use of this technology lends itself to widespread applicability.en_US
dc.identifier.citationLouie, Justin S., Shukla, Richa, Richards-Kortum, Rebecca, et al.. "High-resolution microendoscopy in differentiating neoplastic from non-neoplastic colorectal polyps." <i>Best Practice & Research Clinical Gastroenterology,</i> 29, no. 4 (2015) Elsevier: 663-673. http://dx.doi.org/10.1016/j.bpg.2015.05.011.en_US
dc.identifier.doihttp://dx.doi.org/10.1016/j.bpg.2015.05.011en_US
dc.identifier.urihttps://hdl.handle.net/1911/91974en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.rightsThis is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by Elsevier.en_US
dc.subject.keywordcolon neoplasiaen_US
dc.subject.keywordendoscopyen_US
dc.subject.keywordHRMEen_US
dc.subject.keywordoptical biopsyen_US
dc.titleHigh-resolution microendoscopy in differentiating neoplastic from non-neoplastic colorectal polypsen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpost-printen_US
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