Automated frame selection process for high-resolution microendoscopy

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dc.citation.firstpage46014en_US
dc.citation.issueNumber4en_US
dc.citation.journalTitleJournal of Biomedical Opticsen_US
dc.citation.volumeNumber20en_US
dc.contributor.authorIshijima, Ayumuen_US
dc.contributor.authorSchwarz, Richard A.en_US
dc.contributor.authorShin, Dongsuken_US
dc.contributor.authorMondrik, Sharonen_US
dc.contributor.authorVigneswaran, Nadarajahen_US
dc.contributor.authorGillenwater, Ann M.en_US
dc.contributor.authorAnandasabapathy, Sharmilaen_US
dc.contributor.authorRichards-Kortum, Rebeccaen_US
dc.contributor.orgBioengineeringen_US
dc.date.accessioned2016-06-22T20:08:01Zen_US
dc.date.available2016-06-22T20:08:01Zen_US
dc.date.issued2015en_US
dc.description.abstractWe developed an automated frame selection algorithm for high-resolution microendoscopy video sequences. The algorithm rapidly selects a representative frame with minimal motion artifact from a short video sequence, enabling fully automated image analysis at the point-of-care. The algorithm was evaluated by quantitative comparison of diagnostically relevant image features and diagnostic classification results obtained using automated frame selection versus manual frame selection. A data set consisting of video sequences collected in vivo from 100 oral sites and 167 esophageal sites was used in the analysis. The area under the receiver operating characteristic curve was 0.78 (automated selection) versus 0.82 (manual selection) for oral sites, and 0.93 (automated selection) versus 0.92 (manual selection) for esophageal sites. The implementation of fully automated high-resolution microendoscopy at the point-of-care has the potential to reduce the number of biopsies needed for accurate diagnosis of precancer and cancer in low-resource settings where there may be limited infrastructure and personnel for standard histologic analysis.en_US
dc.identifier.citationIshijima, Ayumu, Schwarz, Richard A., Shin, Dongsuk, et al.. "Automated frame selection process for high-resolution microendoscopy." <i>Journal of Biomedical Optics,</i> 20, no. 4 (2015) SPIE: 046014. http://dx.doi.org/10.1117/1.JBO.20.4.046014.en_US
dc.identifier.doihttp://dx.doi.org/10.1117/1.JBO.20.4.046014en_US
dc.identifier.urihttps://hdl.handle.net/1911/90535en_US
dc.language.isoengen_US
dc.publisherSPIEen_US
dc.rightsPublished by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.en_US
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/us/en_US
dc.titleAutomated frame selection process for high-resolution microendoscopyen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpublisher versionen_US
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