A role for the root cap in root branching revealed by the non-auxin probe naxillin

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dc.citation.firstpage798en_US
dc.citation.journalTitleNature Chemical Biologyen_US
dc.citation.lastpage805en_US
dc.citation.volumeNumber8en_US
dc.contributor.authorDe Rybel, Berten_US
dc.contributor.authorAudenaert, Dominiqueen_US
dc.contributor.authorXuan, Weien_US
dc.contributor.authorOvervoorde, Paulen_US
dc.contributor.authorStrader, Lucia C.en_US
dc.contributor.authorKepinski, Stefanen_US
dc.contributor.authorHoye, Rebeccaen_US
dc.contributor.authorBrisbois, Ronalden_US
dc.contributor.authorParizot, Borisen_US
dc.contributor.authorVanneste, Steffanen_US
dc.contributor.authorLiu, Xingen_US
dc.contributor.authorGilday, Alisonen_US
dc.contributor.authorGraham, Ian A.en_US
dc.contributor.authorNguyen, Longen_US
dc.contributor.authorJansen, Leentjeen_US
dc.contributor.authorNjo, Maria Fransiskaen_US
dc.contributor.authorInze, Dirken_US
dc.contributor.authorBartel, Bonnieen_US
dc.contributor.authorBeeckman, Tomen_US
dc.date.accessioned2013-01-29T19:58:04Zen_US
dc.date.available2014-01-30T06:10:03Zen_US
dc.date.issued2012en_US
dc.description.abstractThe acquisition of water and nutrients by plant roots is a fundamental aspect of agriculture and strongly depends on root architecture. Root branching and expansion of the root system is achieved through the development of lateral roots and is to a large extent controlled by the plant hormone auxin. However, the pleiotropic effects of auxin or auxin-like molecules on root systems complicate the study of lateral root development. Here we describe a small-molecule screen in Arabidopsis thaliana that identified naxillin as what is to our knowledge the first non-auxin-like molecule that promotes root branching. By using naxillin as a chemical tool, we identified a new function for root cap-specific conversion of the auxin precursor indole-3-butyric acid into the active auxin indole-3-acetic acid and uncovered the involvement of the root cap in root branching. Delivery of an auxin precursor in peripheral tissues such as the root cap might represent an important mechanism shaping root architecture.en_US
dc.embargo.terms1 yearen_US
dc.identifier.citationDe Rybel, Bert, Audenaert, Dominique, Xuan, Wei, et al.. "A role for the root cap in root branching revealed by the non-auxin probe naxillin." <i>Nature Chemical Biology,</i> 8, (2012) Nature America, Inc.: 798-805. http://dx.doi.org/10.1038/nchembio.1044.en_US
dc.identifier.doihttp://dx.doi.org/10.1038/nchembio.1044en_US
dc.identifier.urihttps://hdl.handle.net/1911/69858en_US
dc.language.isoengen_US
dc.publisherNature America, Inc.en_US
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.en_US
dc.titleA role for the root cap in root branching revealed by the non-auxin probe naxillinen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpublisher versionen_US
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