Comparing the Role of Mechanical Forces in Vascular and Valvular Calcification Progression
Date
2019
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Frontiers
Abstract
regulator of lysosomal function, or by inducing TFEB activation chemically. Because of its small format, rapidity, sensitivity and reproducibility, the NAG one-step cell assay is suitable for multiple procedures, including the high-throughput screening of chemical libraries to identify modulators of NAG expression, folding and activity, and the investigation of candidate molecules and constructs for applications in enzyme replacement therapy, gene therapy, and combination therapies.
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Gomel, Madeleine A., Lee, Romi and Grande-Allen, K. Jane. "Comparing the Role of Mechanical Forces in Vascular and Valvular Calcification Progression." Frontiers in Cardiovascular Medicine, (2019) Frontiers: https://doi.org/10.3389/fcvm.2018.00197.
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