A Rapid and Sensitive Method for Measuring NAcetylglucosaminidase Activity in Cultured Cells

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2013
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Public Library of Science
Abstract

A rapid and sensitive method to quantitatively assess N-acetylglucosaminidase (NAG) activity in cultured cells is highly desirable for both basic research and clinical studies. NAG activity is deficient in cells from patients with Mucopolysaccharidosis type IIIB (MPS IIIB) due to mutations in NAGLU, the gene that encodes NAG. Currently available

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Mauri, Victor, Lotfi, Parisa, Segatori, Laura, et al.. "A Rapid and Sensitive Method for Measuring NAcetylglucosaminidase Activity in Cultured Cells." PLoS One, 8, no. 6 (2013) Public Library of Science: e68060. http://dx.doi.org/10.1371/journal.pone.0068060.

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