Responsive liquid crystal elastomers for enhanced cell sheet alignment

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dc.contributor.assigneeRice Universityen_US
dc.contributor.publisherUnited States Patent and Trademark Officeen_US
dc.creatorVerduzco, Rafaelen_US
dc.creatorJacot, Jeffrey G.en_US
dc.creatorAdetiba, Oluwatomiyinen_US
dc.creatorAgrawal, Adityaen_US
dc.date.accessioned2017-06-07T20:22:22Zen_US
dc.date.available2017-06-07T20:22:22Zen_US
dc.date.filed2014-07-14en_US
dc.date.issued2017-04-18en_US
dc.description.abstractResponsive, biocompatible substrates are of interest for directing the maturation and function of cells in vitro during cell culture. This can potentially provide cells and tissues with desirable properties for regenerative therapies. The present disclosure provides a scalable approach to attach, align and dynamically load cells on responsive liquid crystal elastomer (LCE) substrates. Monodomain LCEs exhibit reversible shape changes in response to cyclic stimulus, and when immersed in an aqueous medium on top of, for example, resistive heaters, shape changes are fast, reversible and produce minimal temperature changes in the surroundings.en_US
dc.digitization.specificationsThis patent information was downloaded from the US Patent and Trademark website (http://www.uspto.gov/) as image-PDFs. The PDFs were OCRed for access purposesen_US
dc.format.extent42en_US
dc.identifier.citationVerduzco, Rafael, Jacot, Jeffrey G., Adetiba, Oluwatomiyin and Agrawal, Aditya, "Responsive liquid crystal elastomers for enhanced cell sheet alignment." Patent US9625752Bl. issued 2017-04-18. Retrieved from <a href="https://hdl.handle.net/1911/94820">https://hdl.handle.net/1911/94820</a>.en_US
dc.identifier.patentIDUS9625752Blen_US
dc.identifier.urihttps://hdl.handle.net/1911/94820en_US
dc.language.isoengen_US
dc.titleResponsive liquid crystal elastomers for enhanced cell sheet alignmenten_US
dc.typeUtility patenten_US
dc.type.dcmiTexten_US
dc.type.genrepatentsen_US
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