Increasing the stability of recombinant adult human apohemoglobin

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dc.contributor.assigneeRice Universityen_US
dc.contributor.assigneeWisconsin Alumni Research Foundationen_US
dc.contributor.publisherUnited States Patent and Trademark Officeen_US
dc.creatorOlson, John S.en_US
dc.creatorPhillips, George N., Jr.en_US
dc.date.accessioned2015-05-04T19:05:54Zen_US
dc.date.available2015-05-04T19:05:54Zen_US
dc.date.filed2007-03-14en_US
dc.date.issued2010-09-28en_US
dc.description.abstractThe disclosure relates to recombinant adult human apohemoglobin (apo-rHb) in which the stability has been increased by replacement of an amino acid with a counterpart from another organism, such as a deep sea diving mammal. This mutated apo-rHb may be more stable and/or give higher production yields than unmutated adult human apo-rHb. The mutated apo-rHb may be produced in microorganisms, such as E. coli or yeast cells, or animal erythroid cells. Some apo-rHb of the present disclosure may be used as part of a blood substitute.en_US
dc.digitization.specificationsThis patent information was downloaded from the US Patent and Trademark website (http://www.uspto.gov/) as image-PDFs. The PDFs were OCRed for access purposes.en_US
dc.format.extent20 ppen_US
dc.identifier.citationOlson, John S. and Phillips, George N., Jr., "Increasing the stability of recombinant adult human apohemoglobin." Patent US7803912B2. issued 2010-09-28. Retrieved from https://hdl.handle.net/1911/80034.en_US
dc.identifier.patentIDUS7803912B2en_US
dc.identifier.urihttps://hdl.handle.net/1911/80034en_US
dc.language.isoengen_US
dc.titleIncreasing the stability of recombinant adult human apohemoglobinen_US
dc.typeUtility patenten_US
dc.type.dcmiTexten_US
dc.type.genrepatentsen_US
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