Total synthesis of shishijimicin A and analogs thereof

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dc.contributor.assigneeRice Universityen_US
dc.contributor.publisherUnited States Patent and Trademark Officeen_US
dc.creatorNicolaou, Kyriacos C.en_US
dc.creatorLi, Ruofanen_US
dc.creatorLu, Zhaoyongen_US
dc.creatorSohn, Te-iken_US
dc.creatorWoods, Jamesen_US
dc.creatorPitsinos, Emmanouil N.en_US
dc.date.accessioned2020-09-15T16:05:01Zen_US
dc.date.available2020-09-15T16:05:01Zen_US
dc.date.filed2016-06-29en_US
dc.date.issued2020-03-17en_US
dc.description.abstractIn one aspect, the present disclosure provides shishijimicin analogs of the formula: wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. Additionally, antibody drug conjugates of the compounds are also provided.en_US
dc.digitization.specificationsThis patent information was downloaded from the US Patent and Trademark website (http://www.uspto.gov/) as image-PDFs. The PDFs were OCRed for access purposesen_US
dc.format.extent163en_US
dc.identifier.citationNicolaou, Kyriacos C., Li, Ruofan, Lu, Zhaoyong, Sohn, Te-ik, Woods, James and Pitsinos, Emmanouil N., "Total synthesis of shishijimicin A and analogs thereof." Patent US10590158B2. issued 2020-03-17. Retrieved from <a href="https://hdl.handle.net/1911/109345">https://hdl.handle.net/1911/109345</a>.en_US
dc.identifier.patentIDUS10590158B2en_US
dc.identifier.urihttps://hdl.handle.net/1911/109345en_US
dc.language.isoengen_US
dc.titleTotal synthesis of shishijimicin A and analogs thereofen_US
dc.typeUtility patenten_US
dc.type.dcmiTexten_US
dc.type.genrepatentsen_US
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