Total synthesis of shishijimicin A and analogs thereof

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dc.contributor.assigneeRice University
dc.contributor.publisherUnited States Patent and Trademark Office
dc.creatorNicolaou, Kyriacos C.
dc.creatorLi, Ruofan
dc.creatorLu, Zhaoyong
dc.creatorSohn, Te-ik
dc.creatorWoods, James
dc.creatorPitsinos, Emmanouil N.
dc.date.accessioned2020-09-15T16:05:01Z
dc.date.available2020-09-15T16:05:01Z
dc.date.filed2016-06-29
dc.date.issued2020-03-17
dc.description.abstractIn one aspect, the present disclosure provides shishijimicin analogs of the formula: wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. Additionally, antibody drug conjugates of the compounds are also provided.
dc.digitization.specificationsThis patent information was downloaded from the US Patent and Trademark website (http://www.uspto.gov/) as image-PDFs. The PDFs were OCRed for access purposes
dc.format.extent163
dc.identifier.citationNicolaou, Kyriacos C., Li, Ruofan, Lu, Zhaoyong, Sohn, Te-ik, Woods, James and Pitsinos, Emmanouil N., "Total synthesis of shishijimicin A and analogs thereof." Patent US10590158B2. issued 2020-03-17. Retrieved from <a href="https://hdl.handle.net/1911/109345">https://hdl.handle.net/1911/109345</a>.
dc.identifier.patentIDUS10590158B2
dc.identifier.urihttps://hdl.handle.net/1911/109345
dc.language.isoeng
dc.titleTotal synthesis of shishijimicin A and analogs thereof
dc.typeUtility patent
dc.type.dcmiText
dc.type.genrepatents
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